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Neutral ceramidase-active site inhibitor chemotypes and binding modes.
Coant N, Bickel JD, Rahaim R, Otsuka Y, Choi YM, Xu R, Simoes M, Cariello C, Mao C, Saied EM, Arenz C, Spicer TP, Bannister TD, Tonge PJ, Airola MV, Scampavia L, Hannun YA, Rizzo RC, Haley JD. Coant N, et al. Bioorg Chem. 2023 Oct;139:106747. doi: 10.1016/j.bioorg.2023.106747. Epub 2023 Jul 27. Bioorg Chem. 2023. PMID: 37531819 Free PMC article.
Measurement of neutral ceramidase activity in vitro and in vivo.
Simoes M, Saleh A, Choi YM, Airola MV, Haley JD, Coant N. Simoes M, et al. Among authors: coant n. Anal Biochem. 2022 Apr 15;643:114577. doi: 10.1016/j.ab.2022.114577. Epub 2022 Feb 5. Anal Biochem. 2022. PMID: 35134389 Review.
Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening.
Otsuka Y, Airola MV, Choi YM, Coant N, Snider J, Cariello C, Saied EM, Arenz C, Bannister T, Rahaim R Jr, Hannun YA, Shumate J, Scampavia L, Haley JD, Spicer TP. Otsuka Y, et al. Among authors: coant n. SLAS Discov. 2021 Jan;26(1):113-121. doi: 10.1177/2472555220945283. Epub 2020 Jul 31. SLAS Discov. 2021. PMID: 32734807 Free PMC article.
Functions of neutral ceramidase in the Golgi apparatus.
Sakamoto W, Coant N, Canals D, Obeid LM, Hannun YA. Sakamoto W, et al. Among authors: coant n. J Lipid Res. 2018 Nov;59(11):2116-2125. doi: 10.1194/jlr.M088187. Epub 2018 Aug 28. J Lipid Res. 2018. PMID: 30154232 Free PMC article.
31 results