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Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Ren W, Fan H, Grimm SA, Guo Y, Kim JJ, Yin J, Li L, Petell CJ, Tan XF, Zhang ZM, Coan JP, Gao L, Cai L, Detrick B, Çetin B, Cui Q, Strahl BD, Gozani O, Wang Y, Miller KM, O'Leary SE, Wade PA, Patel DJ, Wang GG, Song J. Ren W, et al. Among authors: coan jp. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18439-18447. doi: 10.1073/pnas.2009316117. Epub 2020 Jul 16. Proc Natl Acad Sci U S A. 2020. PMID: 32675241 Free PMC article.
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.
Ren W, Fan H, Grimm SA, Kim JJ, Li L, Guo Y, Petell CJ, Tan XF, Zhang ZM, Coan JP, Yin J, Kim DI, Gao L, Cai L, Khudaverdyan N, Çetin B, Patel DJ, Wang Y, Cui Q, Strahl BD, Gozani O, Miller KM, O'Leary SE, Wade PA, Wang GG, Song J. Ren W, et al. Among authors: coan jp. Nat Commun. 2021 May 3;12(1):2490. doi: 10.1038/s41467-021-22665-4. Nat Commun. 2021. PMID: 33941775 Free PMC article.
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation.
Cheung P, Schaffert S, Chang SE, Dvorak M, Donato M, Macaubas C, Foecke MH, Li TM, Zhang L, Coan JP, Schulert GS, Grom AA, Henderson LA, Nigrovic PA, Elias JE, Gozani O, Mellins ED, Khatri P, Utz PJ, Kuo AJ. Cheung P, et al. Among authors: coan jp. Nat Immunol. 2021 Jun;22(6):711-722. doi: 10.1038/s41590-021-00928-y. Epub 2021 May 20. Nat Immunol. 2021. PMID: 34017121 Free PMC article.
AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Coan JP, Pearson HE, Bahrar H, Fowler TL, Bednarz BP, Saha S, Yang D, Gill PS, Lingen MW, Saloura V, Villaflor VM, Salgia R, Kimple RJ, Wheeler DL. Brand TM, et al. Among authors: coan jp. Clin Cancer Res. 2015 Jun 1;21(11):2601-12. doi: 10.1158/1078-0432.CCR-14-2648. Epub 2015 Mar 12. Clin Cancer Res. 2015. PMID: 25767293 Free PMC article.
Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran PJ, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Iida M, et al. Among authors: coan jp. Mol Cancer Ther. 2016 Sep;15(9):2175-86. doi: 10.1158/1535-7163.MCT-16-0012. Epub 2016 Jul 15. Mol Cancer Ther. 2016. PMID: 27422810 Free PMC article.
15 results