Cloete R - Search Results

1

Aptamer-Based Diagnostic Systems for the Rapid Screening of TB at the Point-of-Care.

Martin DR, Sibuyi NR, Dube P, Fadaka AO, Cloete R, Onani M, Madiehe AM, Meyer M. Martin DR, et al. Among authors: cloete r. Diagnostics (Basel). 2021 Jul 28;11(8):1352. doi: 10.3390/diagnostics11081352. Diagnostics (Basel). 2021. PMID: 34441287 Free PMC article. Review.

2

Structural and functional effects of nucleotide variation on the human TB drug metabolizing enzyme arylamine N-acetyltransferase 1.

Cloete R, Akurugu WA, Werely CJ, van Helden PD, Christoffels A. Cloete R, et al. J Mol Graph Model. 2017 Aug;75:330-339. doi: 10.1016/j.jmgm.2017.04.026. Epub 2017 Jun 10. J Mol Graph Model. 2017. PMID: 28628859 Free article.

3

The determination of the effect(s) of solute carrier family 22-member 2 (SLC22A2) haplotype variants on drug binding via molecular dynamic simulation systems.

Abrahams-October Z, Johnson R, Benjeddou M, Cloete R. Abrahams-October Z, et al. Among authors: cloete r. Sci Rep. 2022 Oct 8;12(1):16936. doi: 10.1038/s41598-022-21291-4. Sci Rep. 2022. PMID: 36209293 Free PMC article.

4

Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c.

Cloete R, Kapp E, Joubert J, Christoffels A, Malan SF. Cloete R, et al. PLoS One. 2018 Nov 26;13(11):e0207605. doi: 10.1371/journal.pone.0207605. eCollection 2018. PLoS One. 2018. PMID: 30475855 Free PMC article.

5

Structure based identification of novel inhibitors against ATP synthase of Mycobacterium tuberculosis: A combined in silico and in vitro study.

Shahbaaz M, Cloete R, Grobbelaar M, Sampson S, Christoffels A. Shahbaaz M, et al. Among authors: cloete r. Int J Biol Macromol. 2019 Aug 15;135:582-590. doi: 10.1016/j.ijbiomac.2019.05.108. Epub 2019 May 20. Int J Biol Macromol. 2019. PMID: 31121229 Free article.

6

In silico repurposing of a Novobiocin derivative for activity against latency associated Mycobacterium tuberculosis drug target nicotinate-nucleotide adenylyl transferase (Rv2421c).

Cloete R, Shahbaaz M, Grobbelaar M, Sampson SL, Christoffels A. Cloete R, et al. PLoS One. 2021 Nov 2;16(11):e0259348. doi: 10.1371/journal.pone.0259348. eCollection 2021. PLoS One. 2021. PMID: 34727137 Free PMC article.

7

Designing a course model for distance-based online bioinformatics training in Africa: The H3ABioNet experience.

Gurwitz KT, Aron S, Panji S, Maslamoney S, Fernandes PL, Judge DP, Ghouila A, Domelevo Entfellner JB, Guerfali FZ, Saunders C, Mansour Alzohairy A, Salifu SP, Ahmed R, Cloete R, Kayondo J, Ssemwanga D, Mulder N; H3ABioNet Consortium's Education Training and Working Group as members of the H3Africa Consortium. Gurwitz KT, et al. Among authors: cloete r. PLoS Comput Biol. 2017 Oct 5;13(10):e1005715. doi: 10.1371/journal.pcbi.1005715. eCollection 2017 Oct. PLoS Comput Biol. 2017. PMID: 28981516 Free PMC article.

8

The Flexible, Extended Coil of the PDZ-Binding Motif of the Three Deadly Human Coronavirus E Proteins Plays a Role in Pathogenicity.

Schoeman D, Cloete R, Fielding BC. Schoeman D, et al. Among authors: cloete r. Viruses. 2022 Aug 2;14(8):1707. doi: 10.3390/v14081707. Viruses. 2022. PMID: 36016329 Free PMC article.

9

Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints.

McEvoy CR, Cloete R, Müller B, Schürch AC, van Helden PD, Gagneux S, Warren RM, Gey van Pittius NC. McEvoy CR, et al. Among authors: cloete r. PLoS One. 2012;7(4):e30593. doi: 10.1371/journal.pone.0030593. Epub 2012 Apr 4. PLoS One. 2012. PMID: 22496726 Free PMC article.

10

Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis.

Cloete R, Oppon E, Murungi E, Schubert WD, Christoffels A. Cloete R, et al. BMC Bioinformatics. 2016 Feb 8;17:75. doi: 10.1186/s12859-016-0898-8. BMC Bioinformatics. 2016. PMID: 26856535 Free PMC article.

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