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Starved epithelial cells uptake extracellular matrix for survival.
Muranen T, Iwanicki MP, Curry NL, Hwang J, DuBois CD, Coloff JL, Hitchcock DS, Clish CB, Brugge JS, Kalaany NY. Muranen T, et al. Among authors: clish cb. Nat Commun. 2017 Jan 10;8:13989. doi: 10.1038/ncomms13989. Nat Commun. 2017. PMID: 28071763 Free PMC article.
Critical role for arginase 2 in obesity-associated pancreatic cancer.
Zaytouni T, Tsai PY, Hitchcock DS, DuBois CD, Freinkman E, Lin L, Morales-Oyarvide V, Lenehan PJ, Wolpin BM, Mino-Kenudson M, Torres EM, Stylopoulos N, Clish CB, Kalaany NY. Zaytouni T, et al. Among authors: clish cb. Nat Commun. 2017 Aug 14;8(1):242. doi: 10.1038/s41467-017-00331-y. Nat Commun. 2017. PMID: 28808255 Free PMC article.
Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population.
Semova I, Levenson AE, Krawczyk J, Bullock K, Williams KA, Wadwa RP, Shah AS, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Bishop FK, Maahs DM, Dolan LM, Clish CB, Biddinger SB. Semova I, et al. Among authors: clish cb. J Clin Lipidol. 2019 Nov-Dec;13(6):940-946. doi: 10.1016/j.jacl.2019.09.008. Epub 2019 Sep 25. J Clin Lipidol. 2019. PMID: 31706902 Free PMC article.
Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes.
Semova I, Levenson AE, Krawczyk J, Bullock K, Williams KA, Wadwa RP, Khoury PR, Kimball TR, Urbina EM, de Ferranti SD, Maahs DM, Dolan LM, Shah AS, Clish CB, Biddinger SB. Semova I, et al. Among authors: clish cb. Pediatr Diabetes. 2020 Nov;21(7):1126-1131. doi: 10.1111/pedi.13097. Epub 2020 Sep 15. Pediatr Diabetes. 2020. PMID: 32738021 Free PMC article.
Insulin Prevents Hypercholesterolemia by Suppressing 12α-Hydroxylated Bile Acids.
Semova I, Levenson AE, Krawczyk J, Bullock K, Gearing ME, Ling AV, Williams KA, Miao J, Adamson SS, Shin DJ, Chahar S, Graham MJ, Crooke RM, Hagey LR, Vicent D, de Ferranti SD, Kidambi S, Clish CB, Biddinger SB. Semova I, et al. Among authors: clish cb. Circulation. 2022 Mar 29;145(13):969-982. doi: 10.1161/CIRCULATIONAHA.120.045373. Epub 2022 Feb 23. Circulation. 2022. PMID: 35193378 Free PMC article. Clinical Trial.
Metabolite profiles and the risk of developing diabetes.
Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, Lewis GD, Fox CS, Jacques PF, Fernandez C, O'Donnell CJ, Carr SA, Mootha VK, Florez JC, Souza A, Melander O, Clish CB, Gerszten RE. Wang TJ, et al. Among authors: clish cb. Nat Med. 2011 Apr;17(4):448-53. doi: 10.1038/nm.2307. Epub 2011 Mar 20. Nat Med. 2011. PMID: 21423183 Free PMC article.
Programming human pluripotent stem cells into white and brown adipocytes.
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA. Ahfeldt T, et al. Among authors: clish cb. Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411. Nat Cell Biol. 2012. PMID: 22246346 Free PMC article.
Distinct metabolomic signatures are associated with longevity in humans.
Cheng S, Larson MG, McCabe EL, Murabito JM, Rhee EP, Ho JE, Jacques PF, Ghorbani A, Magnusson M, Souza AL, Deik AA, Pierce KA, Bullock K, O'Donnell CJ, Melander O, Clish CB, Vasan RS, Gerszten RE, Wang TJ. Cheng S, et al. Among authors: clish cb. Nat Commun. 2015 Apr 13;6:6791. doi: 10.1038/ncomms7791. Nat Commun. 2015. PMID: 25864806 Free PMC article.
479 results