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Understanding the Impact of Resistance to Influenza Antivirals.
Holmes EC, Hurt AC, Dobbie Z, Clinch B, Oxford JS, Piedra PA. Holmes EC, et al. Among authors: clinch b. Clin Microbiol Rev. 2021 Feb 10;34(2):e00224-20. doi: 10.1128/CMR.00224-20. Print 2021 Mar 17. Clin Microbiol Rev. 2021. PMID: 33568554 Free PMC article. Review.
Roche perspectives on Tamiflu.
Clinch B, Smith J. Clinch B, et al. Clin Microbiol Infect. 2015 Mar;21(3):226-9. doi: 10.1016/j.cmi.2015.01.014. Epub 2015 Jan 23. Clin Microbiol Infect. 2015. PMID: 25716982 Free article. Review. No abstract available.
Viral Kinetics and Resistance Development in Children Treated with Neuraminidase Inhibitors: The Influenza Resistance Information Study (IRIS).
Roosenhoff R, Reed V, Kenwright A, Schutten M, Boucher CA, Monto A, Clinch B, Kumar D, Whitley R, Nguyen-Van-Tam JS, Osterhaus ADME, Fouchier RAM, Fraaij PLA. Roosenhoff R, et al. Among authors: clinch b. Clin Infect Dis. 2020 Aug 22;71(5):1186-1194. doi: 10.1093/cid/ciz939. Clin Infect Dis. 2020. PMID: 31560055 Free PMC article.
Baloxavir treatment of ferrets infected with influenza A(H1N1)pdm09 virus reduces onward transmission.
Lee LYY, Zhou J, Frise R, Goldhill DH, Koszalka P, Mifsud EJ, Baba K, Noda T, Ando Y, Sato K, Yuki AI, Shishido T, Uehara T, Wildum S, Zwanziger E, Collinson N, Kuhlbusch K, Clinch B, Hurt AC, Barclay WS. Lee LYY, et al. Among authors: clinch b. PLoS Pathog. 2020 Apr 15;16(4):e1008395. doi: 10.1371/journal.ppat.1008395. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32294137 Free PMC article.
Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2).
Baker J, Block SL, Matharu B, Burleigh Macutkiewicz L, Wildum S, Dimonaco S, Collinson N, Clinch B, Piedra PA. Baker J, et al. Among authors: clinch b. Pediatr Infect Dis J. 2020 Aug;39(8):700-705. doi: 10.1097/INF.0000000000002747. Pediatr Infect Dis J. 2020. PMID: 32516282 Free PMC article. Clinical Trial.
Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS).
Roosenhoff R, Schutten M, Reed V, Clinch B, van der Linden A, Fouchier RAM, Fraaij PLA. Roosenhoff R, et al. Among authors: clinch b. Antiviral Res. 2021 May;189:105060. doi: 10.1016/j.antiviral.2021.105060. Epub 2021 Mar 10. Antiviral Res. 2021. PMID: 33713731 Free article.
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model.
Lee LY, Zhou J, Koszalka P, Frise R, Farrukee R, Baba K, Miah S, Shishido T, Galiano M, Hashimoto T, Omoto S, Uehara T, Mifsud EJ, Collinson N, Kuhlbusch K, Clinch B, Wildum S, Barclay WS, Hurt AC. Lee LY, et al. Among authors: clinch b. PLoS Pathog. 2021 May 6;17(5):e1009527. doi: 10.1371/journal.ppat.1009527. eCollection 2021 May. PLoS Pathog. 2021. PMID: 33956888 Free PMC article.
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