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Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics.
Robles EF, Mena-Varas M, Barrio L, Merino-Cortes SV, Balogh P, Du MQ, Akasaka T, Parker A, Roa S, Panizo C, Martin-Guerrero I, Siebert R, Segura V, Agirre X, Macri-Pellizeri L, Aldaz B, Vilas-Zornoza A, Zhang S, Moody S, Calasanz MJ, Tousseyn T, Broccardo C, Brousset P, Campos-Sanchez E, Cobaleda C, Sanchez-Garcia I, Fernandez-Luna JL, Garcia-Muñoz R, Pena E, Bellosillo B, Salar A, Baptista MJ, Hernandez-Rivas JM, Gonzalez M, Terol MJ, Climent J, Ferrandez A, Sagaert X, Melnick AM, Prosper F, Oscier DG, Carrasco YR, Dyer MJ, Martinez-Climent JA. Robles EF, et al. Among authors: climent j. Nat Commun. 2016 Jun 14;7:11889. doi: 10.1038/ncomms11889. Nat Commun. 2016. PMID: 27297662 Free PMC article.
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.
Sanchez-Izquierdo D, Buchonnet G, Siebert R, Gascoyne RD, Climent J, Karran L, Marin M, Blesa D, Horsman D, Rosenwald A, Staudt LM, Albertson DG, Du MQ, Ye H, Marynen P, Garcia-Conde J, Pinkel D, Dyer MJ, Martinez-Climent JA. Sanchez-Izquierdo D, et al. Among authors: climent j. Blood. 2003 Jun 1;101(11):4539-46. doi: 10.1182/blood-2002-10-3236. Epub 2003 Jan 30. Blood. 2003. PMID: 12560219 Free article.
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome.
Rubio-Moscardo F, Climent J, Siebert R, Piris MA, Martín-Subero JI, Nieländer I, Garcia-Conde J, Dyer MJ, Terol MJ, Pinkel D, Martinez-Climent JA. Rubio-Moscardo F, et al. Among authors: climent j. Blood. 2005 Jun 1;105(11):4445-54. doi: 10.1182/blood-2004-10-3907. Epub 2005 Feb 17. Blood. 2005. PMID: 15718413 Free article.
Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.
Rubio-Moscardo F, Blesa D, Mestre C, Siebert R, Balasas T, Benito A, Rosenwald A, Climent J, Martinez JI, Schilhabel M, Karran EL, Gesk S, Esteller M, deLeeuw R, Staudt LM, Fernandez-Luna JL, Pinkel D, Dyer MJ, Martinez-Climent JA. Rubio-Moscardo F, et al. Among authors: climent j. Blood. 2005 Nov 1;106(9):3214-22. doi: 10.1182/blood-2005-05-2013. Epub 2005 Jul 28. Blood. 2005. PMID: 16051735 Free article.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Mestre-Escorihuela C, Rubio-Moscardo F, Richter JA, Siebert R, Climent J, Fresquet V, Beltran E, Agirre X, Marugan I, Marín M, Rosenwald A, Sugimoto KJ, Wheat LM, Karran EL, García JF, Sanchez L, Prosper F, Staudt LM, Pinkel D, Dyer MJ, Martinez-Climent JA. Mestre-Escorihuela C, et al. Among authors: climent j. Blood. 2007 Jan 1;109(1):271-80. doi: 10.1182/blood-2006-06-026500. Epub 2006 Sep 7. Blood. 2007. PMID: 16960149 Free article.
Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma.
Martinez-Climent JA, Vizcarra E, Sanchez D, Blesa D, Marugan I, Benet I, Sole F, Rubio-Moscardo F, Terol MJ, Climent J, Sarsotti E, Tormo M, Andreu E, Salido M, Ruiz MA, Prosper F, Siebert R, Dyer MJ, García-Conde J. Martinez-Climent JA, et al. Among authors: climent j. Blood. 2001 Dec 1;98(12):3479-82. doi: 10.1182/blood.v98.12.3479. Blood. 2001. PMID: 11719392 Free article.
113 results