Clevers H - Search Results

1

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity.

Kopper O, de Witte CJ, Lõhmussaar K, Valle-Inclan JE, Hami N, Kester L, Balgobind AV, Korving J, Proost N, Begthel H, van Wijk LM, Revilla SA, Theeuwsen R, van de Ven M, van Roosmalen MJ, Ponsioen B, Ho VWH, Neel BG, Bosse T, Gaarenstroom KN, Vrieling H, Vreeswijk MPG, van Diest PJ, Witteveen PO, Jonges T, Bos JL, van Oudenaarden A, Zweemer RP, Snippert HJG, Kloosterman WP, Clevers H. Kopper O, et al. Among authors: clevers h. Nat Med. 2019 May;25(5):838-849. doi: 10.1038/s41591-019-0422-6. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011202

2

Canonical Wnt signals are essential for homeostasis of the intestinal epithelium.

Pinto D, Gregorieff A, Begthel H, Clevers H. Pinto D, et al. Among authors: clevers h. Genes Dev. 2003 Jul 15;17(14):1709-13. doi: 10.1101/gad.267103. Genes Dev. 2003. PMID: 12865297 Free PMC article.

3

The Wnt/beta-catenin pathway regulates cardiac valve formation.

Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H. Hurlstone AF, et al. Among authors: clevers h. Nature. 2003 Oct 9;425(6958):633-7. doi: 10.1038/nature02028. Nature. 2003. PMID: 14534590 Free article.

4

De novo crypt formation and juvenile polyposis on BMP inhibition in mouse intestine.

Haramis AP, Begthel H, van den Born M, van Es J, Jonkheer S, Offerhaus GJ, Clevers H. Haramis AP, et al. Among authors: clevers h. Science. 2004 Mar 12;303(5664):1684-6. doi: 10.1126/science.1093587. Science. 2004. PMID: 15017003

5

Down-regulation of Rap1 activity is involved in ephrinB1-induced cell contraction.

Riedl JA, Brandt DT, Batlle E, Price LS, Clevers H, Bos JL. Riedl JA, et al. Among authors: clevers h. Biochem J. 2005 Jul 15;389(Pt 2):465-9. doi: 10.1042/BJ20050048. Biochem J. 2005. PMID: 15725075 Free PMC article.

6

Wnt signalling induces maturation of Paneth cells in intestinal crypts.

van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, Clevers H. van Es JH, et al. Among authors: clevers h. Nat Cell Biol. 2005 Apr;7(4):381-6. doi: 10.1038/ncb1240. Epub 2005 Mar 20. Nat Cell Biol. 2005. PMID: 15778706

7

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells.

van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H. van Es JH, et al. Among authors: clevers h. Nature. 2005 Jun 16;435(7044):959-63. doi: 10.1038/nature03659. Nature. 2005. PMID: 15959515

8

EphB receptor activity suppresses colorectal cancer progression.

Batlle E, Bacani J, Begthel H, Jonkheer S, Gregorieff A, van de Born M, Malats N, Sancho E, Boon E, Pawson T, Gallinger S, Pals S, Clevers H. Batlle E, et al. Among authors: clevers h. Nature. 2005 Jun 23;435(7045):1126-30. doi: 10.1038/nature03626. Nature. 2005. PMID: 15973414

9

Expression pattern of Wnt signaling components in the adult intestine.

Gregorieff A, Pinto D, Begthel H, Destrée O, Kielman M, Clevers H. Gregorieff A, et al. Among authors: clevers h. Gastroenterology. 2005 Aug;129(2):626-38. doi: 10.1016/j.gastro.2005.06.007. Gastroenterology. 2005. PMID: 16083717

10

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis AP, Hurlstone A, van der Velden Y, Begthel H, van den Born M, Offerhaus GJ, Clevers HC. Haramis AP, et al. Among authors: clevers hc. EMBO Rep. 2006 Apr;7(4):444-9. doi: 10.1038/sj.embor.7400638. Epub 2006 Jan 27. EMBO Rep. 2006. PMID: 16439994 Free PMC article.

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