Clemons PA - Search Results

1

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles.

Eaton JK, Furst L, Ruberto RA, Moosmayer D, Hilpmann A, Ryan MJ, Zimmermann K, Cai LL, Niehues M, Badock V, Kramm A, Chen S, Hillig RC, Clemons PA, Gradl S, Montagnon C, Lazarski KE, Christian S, Bajrami B, Neuhaus R, Eheim AL, Viswanathan VS, Schreiber SL. Eaton JK, et al. Among authors: clemons pa. Nat Chem Biol. 2020 May;16(5):497-506. doi: 10.1038/s41589-020-0501-5. Epub 2020 Mar 30. Nat Chem Biol. 2020. PMID: 32231343 Free PMC article.

2

Exploiting site-site interactions on solid support to generate dimeric molecules.

Blackwell HE, Clemons PA, Schreiber SL. Blackwell HE, et al. Among authors: clemons pa. Org Lett. 2001 Apr 19;3(8):1185-8. doi: 10.1021/ol015647i. Org Lett. 2001. PMID: 11348190

3

A one-bead, one-stock solution approach to chemical genetics: part 2.

Clemons PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, Foley MA. Clemons PA, et al. Chem Biol. 2001 Dec;8(12):1183-95. doi: 10.1016/s1074-5521(01)00086-2. Chem Biol. 2001. PMID: 11755397

4

Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.

Clemons PA, Gladstone BG, Seth A, Chao ED, Foley MA, Schreiber SL. Clemons PA, et al. Chem Biol. 2002 Jan;9(1):49-61. doi: 10.1016/s1074-5521(02)00085-6. Chem Biol. 2002. PMID: 11841938

5

Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations.

Haggarty SJ, Clemons PA, Schreiber SL. Haggarty SJ, et al. Among authors: clemons pa. J Am Chem Soc. 2003 Sep 3;125(35):10543-5. doi: 10.1021/ja035413p. J Am Chem Soc. 2003. PMID: 12940736

6

Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space.

Kim YK, Arai MA, Arai T, Lamenzo JO, Dean EF 3rd, Patterson N, Clemons PA, Schreiber SL. Kim YK, et al. Among authors: clemons pa. J Am Chem Soc. 2004 Nov 17;126(45):14740-5. doi: 10.1021/ja048170p. J Am Chem Soc. 2004. PMID: 15535697

7

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.

Haggarty SJ, Clemons PA, Wong JC, Schreiber SL. Haggarty SJ, et al. Among authors: clemons pa. Comb Chem High Throughput Screen. 2004 Nov;7(7):669-76. doi: 10.2174/1386207043328319. Comb Chem High Throughput Screen. 2004. PMID: 15578929 Review.

8

SpectralNET--an application for spectral graph analysis and visualization.

Forman JJ, Clemons PA, Schreiber SL, Haggarty SJ. Forman JJ, et al. Among authors: clemons pa. BMC Bioinformatics. 2005 Oct 19;6:260. doi: 10.1186/1471-2105-6-260. BMC Bioinformatics. 2005. PMID: 16236170 Free PMC article.

9

Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.

Tolliday N, Clemons PA, Ferraiolo P, Koehler AN, Lewis TA, Li X, Schreiber SL, Gerhard DS, Eliasof S. Tolliday N, et al. Among authors: clemons pa. Cancer Res. 2006 Sep 15;66(18):8935-42. doi: 10.1158/0008-5472.CAN-06-2552. Cancer Res. 2006. PMID: 16982730 Free article.

10

ChemBank: a small-molecule screening and cheminformatics resource database.

Seiler KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S, Brudz S, Sullivan JP, Muhlich J, Serrano M, Ferraiolo P, Tolliday NJ, Schreiber SL, Clemons PA. Seiler KP, et al. Among authors: clemons pa. Nucleic Acids Res. 2008 Jan;36(Database issue):D351-9. doi: 10.1093/nar/gkm843. Epub 2007 Oct 18. Nucleic Acids Res. 2008. PMID: 17947324 Free PMC article.

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