Clausen JD - Search Results

1

SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation.

Clausen JD, Bublitz M, Arnou B, Montigny C, Jaxel C, Møller JV, Nissen P, Andersen JP, le Maire M. Clausen JD, et al. EMBO J. 2013 Dec 11;32(24):3231-43. doi: 10.1038/emboj.2013.250. Epub 2013 Nov 22. EMBO J. 2013. PMID: 24270570 Free PMC article.

2

Roles of Leu249, Lys252, and Leu253 in membrane segment M3 of sarcoplasmic reticulum Ca2+-ATPase in control of Ca2+ migration and long-range intramolecular communication.

Clausen JD, Andersen JP. Clausen JD, et al. Biochemistry. 2003 Mar 11;42(9):2585-94. doi: 10.1021/bi0271897. Biochemistry. 2003. PMID: 12614153

3

Functional consequences of alterations to Thr247, Pro248, Glu340, Asp813, Arg819, and Arg822 at the interfaces between domain P, M3, and L6-7 of sarcoplasmic reticulum Ca2+-ATPase. Roles in Ca2+ interaction and phosphoenzyme processing.

Clausen JD, Andersen JP. Clausen JD, et al. J Biol Chem. 2004 Dec 24;279(52):54426-37. doi: 10.1074/jbc.M410204200. Epub 2004 Oct 12. J Biol Chem. 2004. PMID: 15485864 Free article.

4

Glutamate 90 at the luminal ion gate of sarcoplasmic reticulum Ca2+-ATPase is critical for Ca(2+) binding on both sides of the membrane.

Clausen JD, Andersen JP. Clausen JD, et al. J Biol Chem. 2010 Jul 2;285(27):20780-92. doi: 10.1074/jbc.M110.116459. Epub 2010 Apr 26. J Biol Chem. 2010. PMID: 20421308 Free PMC article.

5

Critical roles of interdomain interactions for modulatory ATP binding to sarcoplasmic reticulum Ca2+-ATPase.

Clausen JD, Holdensen AN, Andersen JP. Clausen JD, et al. J Biol Chem. 2014 Oct 17;289(42):29123-34. doi: 10.1074/jbc.M114.571687. Epub 2014 Sep 5. J Biol Chem. 2014. PMID: 25193668 Free PMC article.

6

Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.

Clausen JD, Bublitz M, Arnou B, Olesen C, Andersen JP, Møller JV, Nissen P. Clausen JD, et al. Structure. 2016 Apr 5;24(4):617-623. doi: 10.1016/j.str.2016.02.018. Structure. 2016. PMID: 27050689 Free article.

7

The SERCA residue Glu340 mediates interdomain communication that guides Ca²⁺ transport.

Geurts MMG, Clausen JD, Arnou B, Montigny C, Lenoir G, Corey RA, Jaxel C, Møller JV, Nissen P, Andersen JP, le Maire M, Bublitz M. Geurts MMG, et al. Among authors: clausen jd. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31114-31122. doi: 10.1073/pnas.2014896117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229570 Free PMC article.

8

Importance of conserved N-domain residues Thr441, Glu442, Lys515, Arg560, and Leu562 of sarcoplasmic reticulum Ca2+-ATPase for MgATP binding and subsequent catalytic steps. Plasticity of the nucleotide-binding site.

Clausen JD, McIntosh DB, Vilsen B, Woolley DG, Andersen JP. Clausen JD, et al. J Biol Chem. 2003 May 30;278(22):20245-58. doi: 10.1074/jbc.M301122200. Epub 2003 Mar 20. J Biol Chem. 2003. PMID: 12649284 Free article.

9

Mutagenesis of residues involved in control of the Ca2+ entry pathway and conformational changes associated with Ca2+ binding in the SR Ca2+-ATPase.

Andersen JP, Clausen JD, Einholm AP, Vilsen B. Andersen JP, et al. Among authors: clausen jd. Ann N Y Acad Sci. 2003 Apr;986:72-81. doi: 10.1111/j.1749-6632.2003.tb07141.x. Ann N Y Acad Sci. 2003. PMID: 12763777

10

Mutational analysis of Lys252 and its interaction with loop 6-7 in the SR Ca2+-ATPase.

Clausen JD, Andersen JP. Clausen JD, et al. Ann N Y Acad Sci. 2003 Apr;986:335-7. doi: 10.1111/j.1749-6632.2003.tb07207.x. Ann N Y Acad Sci. 2003. PMID: 12763843 No abstract available.

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