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Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models.
Puliga E, De Bellis C, Vietti Michelina S, Capeloa T, Migliore C, Orrù C, Baiocchi GL, De Manzoni G, Pietrantonio F, Reddavid R, Fumagalli Romario U, Ambrogio C, Corso S, Giordano S. Puliga E, et al. Among authors: orru c. Gastric Cancer. 2024 May;27(3):473-483. doi: 10.1007/s10120-024-01468-8. Epub 2024 Jan 23. Gastric Cancer. 2024. PMID: 38261067 Free PMC article.
BRCA2 Germline Mutations Identify Gastric Cancers Responsive to PARP Inhibitors.
Petrelli A, Rizzolio S, Pietrantonio F, Bellomo SE, Benelli M, De Cecco L, Romagnoli D, Berrino E, Orrù C, Ribisi S, Moya-Rull D, Migliore C, Conticelli D, Maina IM, Puliga E, Serra V, Pellegrino B, Llop-Guevara A, Musolino A, Siena S, Sartore-Bianchi A, Prisciandaro M, Morano F, Antista M, Fumagalli U, De Manzoni G, Degiuli M, Baiocchi GL, Amisano MF, Ferrero A, Marchiò C, Corso S, Giordano S. Petrelli A, et al. Among authors: orru c. Cancer Res. 2023 May 15;83(10):1699-1710. doi: 10.1158/0008-5472.CAN-22-2620. Cancer Res. 2023. PMID: 37129948 Free PMC article.
Nrf2 in Neoplastic and Non-Neoplastic Liver Diseases.
Orrù C, Giordano S, Columbano A. Orrù C, et al. Cancers (Basel). 2020 Oct 12;12(10):2932. doi: 10.3390/cancers12102932. Cancers (Basel). 2020. PMID: 33053665 Free PMC article. Review.
Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming.
Kowalik MA, Puliga E, Cabras L, Sulas P, Petrelli A, Perra A, Ledda-Columbano GM, Morandi A, Merlin S, Orrù C, Sanchez-Martin C, Fornari F, Gramantieri L, Parri M, Rasola A, Bellomo SE, Sebastian C, Follenzi A, Giordano S, Columbano A. Kowalik MA, et al. Among authors: orru c. J Hepatol. 2020 Jun;72(6):1159-1169. doi: 10.1016/j.jhep.2019.12.018. Epub 2020 Jan 15. J Hepatol. 2020. PMID: 31954205