Clarkson M - Search Results

1

Structural Dynamics of the Activation of Elongation Factor 2 Kinase by Ca²⁺-Calmodulin.

Will N, Lee K, Hajredini F, Giles DH, Abzalimov RR, Clarkson M, Dalby KN, Ghose R. Will N, et al. Among authors: clarkson m. J Mol Biol. 2018 Aug 17;430(17):2802-2821. doi: 10.1016/j.jmb.2018.05.033. Epub 2018 May 22. J Mol Biol. 2018. PMID: 29800565 Free PMC article.

2

Ligand binding reduces conformational flexibility in the active site of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonasaeruginosa.

Koveal D, Clarkson MW, Wood TK, Page R, Peti W. Koveal D, et al. J Mol Biol. 2013 Jun 26;425(12):2219-31. doi: 10.1016/j.jmb.2013.03.023. Epub 2013 Mar 21. J Mol Biol. 2013. PMID: 23524133 Free PMC article.

3

Evidence against the "Y-T coupling" mechanism of activation in the response regulator NtrC.

Villali J, Pontiggia F, Clarkson MW, Hagan MF, Kern D. Villali J, et al. J Mol Biol. 2014 Apr 3;426(7):1554-67. doi: 10.1016/j.jmb.2013.12.027. Epub 2014 Jan 7. J Mol Biol. 2014. PMID: 24406745 Free PMC article.

4

Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR.

Bosco DA, Eisenmesser EZ, Clarkson MW, Wolf-Watz M, Labeikovsky W, Millet O, Kern D. Bosco DA, et al. Among authors: clarkson mw. J Mol Biol. 2010 Nov 12;403(5):723-38. doi: 10.1016/j.jmb.2010.08.001. Epub 2010 Aug 12. J Mol Biol. 2010. PMID: 20708627

5

Cooperative dynamics across distinct structural elements regulate PTP1B activity.

Torgeson KR, Clarkson MW, Kumar GS, Page R, Peti W. Torgeson KR, et al. J Biol Chem. 2020 Oct 2;295(40):13829-13837. doi: 10.1074/jbc.RA120.014652. Epub 2020 Jul 31. J Biol Chem. 2020. PMID: 32737198 Free PMC article.

6

Conserved conformational dynamics determine enzyme activity.

Torgeson KR, Clarkson MW, Granata D, Lindorff-Larsen K, Page R, Peti W. Torgeson KR, et al. Sci Adv. 2022 Aug 5;8(31):eabo5546. doi: 10.1126/sciadv.abo5546. Epub 2022 Aug 3. Sci Adv. 2022. PMID: 35921420 Free PMC article.

7

Dynamic activation and regulation of the mitogen-activated protein kinase p38.

Kumar GS, Clarkson MW, Kunze MBA, Granata D, Wand AJ, Lindorff-Larsen K, Page R, Peti W. Kumar GS, et al. Proc Natl Acad Sci U S A. 2018 May 1;115(18):4655-4660. doi: 10.1073/pnas.1721441115. Epub 2018 Apr 16. Proc Natl Acad Sci U S A. 2018. PMID: 29666261 Free PMC article.

8

NMR Based SARS-CoV-2 Antibody Screening.

Schoenle MV, Li Y, Yuan M, Clarkson MW, Wilson IA, Peti W, Page R. Schoenle MV, et al. Among authors: clarkson mw. J Am Chem Soc. 2021 Jun 2;143(21):7930-7934. doi: 10.1021/jacs.1c03945. Epub 2021 May 21. J Am Chem Soc. 2021. PMID: 34018723

9

Retinoic Acid Binding Leads to CRABP2 Rigidification and Dimerization.

Lixa C, Clarkson MW, Iqbal A, Moon TM, Almeida FCL, Peti W, Pinheiro AS. Lixa C, et al. Among authors: clarkson mw. Biochemistry. 2019 Oct 15;58(41):4183-4194. doi: 10.1021/acs.biochem.9b00672. Epub 2019 Oct 7. Biochemistry. 2019. PMID: 31566355

10

Mesodynamics in the SARS nucleocapsid measured by NMR field cycling.

Clarkson MW, Lei M, Eisenmesser EZ, Labeikovsky W, Redfield A, Kern D. Clarkson MW, et al. J Biomol NMR. 2009 Sep;45(1-2):217-25. doi: 10.1007/s10858-009-9347-6. Epub 2009 Jul 30. J Biomol NMR. 2009. PMID: 19641854 Free PMC article.

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