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A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PAF, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S; Psychiatric Genomics Consortium Substance Use Disorders Workgroup; Davis LK, Bogdan R, Geler… See abstract for full author list ➔ Johnson EC, et al. Among authors: clarke tk. Lancet Psychiatry. 2020 Dec;7(12):1032-1045. doi: 10.1016/S2215-0366(20)30339-4. Epub 2020 Oct 20. Lancet Psychiatry. 2020. PMID: 33096046 Free PMC article.
Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.
Schumann G, Johann M, Frank J, Preuss U, Dahmen N, Laucht M, Rietschel M, Rujescu D, Lourdusamy A, Clarke TK, Krause K, Dyer A, Depner M, Wellek S, Treutlein J, Szegedi A, Giegling I, Cichon S, Blomeyer D, Heinz A, Heath S, Lathrop M, Wodarz N, Soyka M, Spanagel R, Mann K. Schumann G, et al. Among authors: clarke tk. Arch Gen Psychiatry. 2008 Jul;65(7):826-38. doi: 10.1001/archpsyc.65.7.826. Arch Gen Psychiatry. 2008. PMID: 18606955
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esko T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, D… See abstract for full author list ➔ Schumann G, et al. Among authors: clarke tk. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7119-24. doi: 10.1073/pnas.1017288108. Epub 2011 Apr 6. Proc Natl Acad Sci U S A. 2011. PMID: 21471458 Free PMC article.
Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.
Dong L, Bilbao A, Laucht M, Henriksson R, Yakovleva T, Ridinger M, Desrivieres S, Clarke TK, Lourdusamy A, Smolka MN, Cichon S, Blomeyer D, Treutlein J, Perreau-Lenz S, Witt S, Leonardi-Essmann F, Wodarz N, Zill P, Soyka M, Albrecht U, Rietschel M, Lathrop M, Bakalkin G, Spanagel R, Schumann G. Dong L, et al. Among authors: clarke tk. Am J Psychiatry. 2011 Oct;168(10):1090-8. doi: 10.1176/appi.ajp.2011.10111579. Epub 2011 Aug 9. Am J Psychiatry. 2011. PMID: 21828288 Free article.
Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort.
Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM. Clarke TK, et al. Addict Biol. 2016 Mar;21(2):469-80. doi: 10.1111/adb.12245. Epub 2015 Apr 10. Addict Biol. 2016. PMID: 25865819 Free PMC article.
Polygenic risk for coronary artery disease is associated with cognitive ability in older adults.
Hagenaars SP, Harris SE, Clarke TK, Hall L, Luciano M, Fernandez-Pujals AM, Davies G, Hayward C; Generation Scotland; Starr JM, Porteous DJ, McIntosh AM, Deary IJ. Hagenaars SP, et al. Among authors: clarke tk. Int J Epidemiol. 2016 Apr;45(2):433-440. doi: 10.1093/ije/dyv354. Epub 2016 Jan 28. Int J Epidemiol. 2016. PMID: 26822939 Free PMC article.
A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder.
Zeng Y, Navarro P, Fernandez-Pujals AM, Hall LS, Clarke TK, Thomson PA, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, MacIntyre DJ, Wray NR; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Deary IJ, Porteous DJ, Haley CS, McIntosh AM. Zeng Y, et al. Among authors: clarke tk. Biol Psychiatry. 2017 Feb 15;81(4):336-346. doi: 10.1016/j.biopsych.2016.04.017. Epub 2016 May 2. Biol Psychiatry. 2017. PMID: 27422368 Free PMC article.
151 results