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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy.
Yamamoto J, Inubushi S, Han Q, Tashiro Y, Sugisawa N, Hamada K, Aoki Y, Miyake K, Matsuyama R, Bouvet M, Clarke SG, Endo I, Hoffman RM. Yamamoto J, et al. Among authors: clarke sg. iScience. 2022 Mar 25;25(4):104162. doi: 10.1016/j.isci.2022.104162. eCollection 2022 Apr 15. iScience. 2022. PMID: 35434545 Free PMC article.
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and alteration of histone-H3 lysine-methylation.
Aoki Y, Han Q, Tome Y, Yamamoto J, Kubota Y, Masaki N, Obara K, Hamada K, Wang JD, Inubushi S, Bouvet M, Clarke SG, Nishida K, Hoffman RM. Aoki Y, et al. Among authors: clarke sg. Front Oncol. 2022 Nov 3;12:1009548. doi: 10.3389/fonc.2022.1009548. eCollection 2022. Front Oncol. 2022. PMID: 36408173 Free PMC article.
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor.
Feoli A, Iannelli G, Cipriano A, Milite C, Shen L, Wang Z, Hadjikyriacou A, Lowe TL, Safaeipour C, Viviano M, Sarno G, Morretta E, Monti MC, Yang Y, Clarke SG, Cosconati S, Castellano S, Sbardella G. Feoli A, et al. Among authors: clarke sg. J Med Chem. 2023 Oct 12;66(19):13665-13683. doi: 10.1021/acs.jmedchem.3c01030. Epub 2023 Aug 10. J Med Chem. 2023. PMID: 37560786 Free PMC article.
111 results