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Symmetric activation and modulation of the human calcium-sensing receptor.
Park J, Zuo H, Frangaj A, Fu Z, Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ, Eng E, Lee Y, Kloss B, Liu Z, Hendrickson WA, Potter CS, Carragher B, Graziano J, Conigrave AD, Frank J, Clarke OB, Fan QR. Park J, et al. Among authors: clarke ob. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2115849118. doi: 10.1073/pnas.2115849118. Proc Natl Acad Sci U S A. 2021. PMID: 34916296 Free PMC article.
Structural basis for catalysis in a CDP-alcohol phosphotransferase.
Sciara G, Clarke OB, Tomasek D, Kloss B, Tabuso S, Byfield R, Cohn R, Banerjee S, Rajashankar KR, Slavkovic V, Graziano JH, Shapiro L, Mancia F. Sciara G, et al. Among authors: clarke ob. Nat Commun. 2014 Jun 13;5:4068. doi: 10.1038/ncomms5068. Nat Commun. 2014. PMID: 24923293 Free PMC article.
Structure of a mammalian ryanodine receptor.
Zalk R, Clarke OB, des Georges A, Grassucci RA, Reiken S, Mancia F, Hendrickson WA, Frank J, Marks AR. Zalk R, et al. Among authors: clarke ob. Nature. 2015 Jan 1;517(7532):44-9. doi: 10.1038/nature13950. Epub 2014 Dec 1. Nature. 2015. PMID: 25470061 Free PMC article.
Structural basis for phosphatidylinositol-phosphate biosynthesis.
Clarke OB, Tomasek D, Jorge CD, Dufrisne MB, Kim M, Banerjee S, Rajashankar KR, Shapiro L, Hendrickson WA, Santos H, Mancia F. Clarke OB, et al. Nat Commun. 2015 Oct 16;6:8505. doi: 10.1038/ncomms9505. Nat Commun. 2015. PMID: 26510127 Free PMC article.
Structure of the STRA6 receptor for retinol uptake.
Chen Y, Clarke OB, Kim J, Stowe S, Kim YK, Assur Z, Cavalier M, Godoy-Ruiz R, von Alpen DC, Manzini C, Blaner WS, Frank J, Quadro L, Weber DJ, Shapiro L, Hendrickson WA, Mancia F. Chen Y, et al. Among authors: clarke ob. Science. 2016 Aug 26;353(6302):aad8266. doi: 10.1126/science.aad8266. Science. 2016. PMID: 27563101 Free PMC article.
Structural Basis for Gating and Activation of RyR1.
des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. des Georges A, et al. Among authors: clarke ob. Cell. 2016 Sep 22;167(1):145-157.e17. doi: 10.1016/j.cell.2016.08.075. Cell. 2016. PMID: 27662087 Free PMC article.
Structures of the colossal RyR1 calcium release channel.
Clarke OB, Hendrickson WA. Clarke OB, et al. Curr Opin Struct Biol. 2016 Aug;39:144-152. doi: 10.1016/j.sbi.2016.09.002. Epub 2016 Sep 27. Curr Opin Struct Biol. 2016. PMID: 27687475 Free PMC article. Review.
Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.
Hartel AJW, Ong P, Schroeder I, Giese MH, Shekar S, Clarke OB, Zalk R, Marks AR, Hendrickson WA, Shepard KL. Hartel AJW, et al. Among authors: clarke ob. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1789-E1798. doi: 10.1073/pnas.1712313115. Epub 2018 Feb 5. Proc Natl Acad Sci U S A. 2018. PMID: 29432144 Free PMC article.
Structure-based analysis of CysZ-mediated cellular uptake of sulfate.
Assur Sanghai Z, Liu Q, Clarke OB, Belcher-Dufrisne M, Wiriyasermkul P, Giese MH, Leal-Pinto E, Kloss B, Tabuso S, Love J, Punta M, Banerjee S, Rajashankar KR, Rost B, Logothetis D, Quick M, Hendrickson WA, Mancia F. Assur Sanghai Z, et al. Among authors: clarke ob. Elife. 2018 May 24;7:e27829. doi: 10.7554/eLife.27829. Elife. 2018. PMID: 29792261 Free PMC article.
63 results