Clarke J - Search Results

1

Mechanistic Modeling of In Vitro Skin Permeation and Extrapolation to In Vivo for Topically Applied Metronidazole Drug Products Using a Physiologically Based Pharmacokinetic Model.

Arora S, Clarke J, Tsakalozou E, Ghosh P, Alam K, Grice JE, Roberts MS, Jamei M, Polak S. Arora S, et al. Among authors: clarke j. Mol Pharm. 2022 Sep 5;19(9):3139-3152. doi: 10.1021/acs.molpharmaceut.2c00229. Epub 2022 Aug 15. Mol Pharm. 2022. PMID: 35969125

2

Multi-phase multi-layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin.

Patel N, Clarke JF, Salem F, Abdulla T, Martins F, Arora S, Tsakalozou E, Hodgkinson A, Arjmandi-Tash O, Cristea S, Ghosh P, Alam K, Raney SG, Jamei M, Polak S. Patel N, et al. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):1060-1084. doi: 10.1002/psp4.12814. Epub 2022 Jun 27. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35670226 Free PMC article.

3

An open-access data set of pig skin anatomy and physiology for modelling purposes.

Krumpholz L, Clarke JF, Polak S, Wiśniowska B. Krumpholz L, et al. Database (Oxford). 2022 Oct 8;2022:baac091. doi: 10.1093/database/baac091. Database (Oxford). 2022. PMID: 36208224 Free PMC article.

4

A mechanistic physiologically based model to assess the effect of study design and modified physiology on formulation safe space for virtual bioequivalence of dermatological drug products.

Clarke JF, Thakur K, Polak S. Clarke JF, et al. Front Pharmacol. 2022 Dec 1;13:1007496. doi: 10.3389/fphar.2022.1007496. eCollection 2022. Front Pharmacol. 2022. PMID: 36532731 Free PMC article.

5

Dermal Absorption of Pesticide Residues.

Clarke JF, Cordery SF, Morgan NA, Knowles PK, Guy RH. Clarke JF, et al. Chem Res Toxicol. 2018 Dec 17;31(12):1356-1363. doi: 10.1021/acs.chemrestox.8b00227. Epub 2018 Dec 6. Chem Res Toxicol. 2018. PMID: 30468381

6

Comparing natural language processing representations of coded disease sequences for prediction in electronic health records.

Beaney T, Jha S, Alaa A, Smith A, Clarke J, Woodcock T, Majeed A, Aylin P, Barahona M. Beaney T, et al. Among authors: clarke j. J Am Med Inform Assoc. 2024 May 8:ocae091. doi: 10.1093/jamia/ocae091. Online ahead of print. J Am Med Inform Assoc. 2024. PMID: 38719204

7

P-wave alternans rebound following pulmonary vein isolation predicts atrial arrhythmia recurrence.

Nearing BD, Fialho GL, Waks JW, Maher TR, Clarke JR, Shepherd AJ, D'Avila A, Verrier RL. Nearing BD, et al. Among authors: clarke jr. J Cardiovasc Electrophysiol. 2024 May 7. doi: 10.1111/jce.16291. Online ahead of print. J Cardiovasc Electrophysiol. 2024. PMID: 38715310

8

Assessing the stability and sporicidal efficacy of oxidising disinfectants.

Brown L, Marshall A, Conway L, Otter J, Norville P, Clarke J. Brown L, et al. Among authors: clarke j. J Hosp Infect. 2024 May 3:S0195-6701(24)00151-8. doi: 10.1016/j.jhin.2024.04.010. Online ahead of print. J Hosp Infect. 2024. PMID: 38705474

9

Genotypic analysis of a localised hotspot of Pestivirus A (BVDV-1) infections in Northern Ireland.

McConville J, Allen A, Moyce A, Donaghy A, Clarke J, Guelbenzu-Gonzalo M, Byrne AW, Verner S, Strain S, McInerney B, Holmes E. McConville J, et al. Among authors: clarke j. Vet Rec. 2024 May 1:e4150. doi: 10.1002/vetr.4150. Online ahead of print. Vet Rec. 2024. PMID: 38693629

10

Probing single electrons across 300-mm spin qubit wafers.

Neyens S, Zietz OK, Watson TF, Luthi F, Nethwewala A, George HC, Henry E, Islam M, Wagner AJ, Borjans F, Connors EJ, Corrigan J, Curry MJ, Keith D, Kotlyar R, Lampert LF, Mądzik MT, Millard K, Mohiyaddin FA, Pellerano S, Pillarisetty R, Ramsey M, Savytskyy R, Schaal S, Zheng G, Ziegler J, Bishop NC, Bojarski S, Roberts J, Clarke JS. Neyens S, et al. Among authors: clarke js. Nature. 2024 May;629(8010):80-85. doi: 10.1038/s41586-024-07275-6. Epub 2024 May 1. Nature. 2024. PMID: 38693414 Free PMC article.

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