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Structure-guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release.
Foster TL, Thompson GS, Kalverda AP, Kankanala J, Bentham M, Wetherill LF, Thompson J, Barker AM, Clarke D, Noerenberg M, Pearson AR, Rowlands DJ, Homans SW, Harris M, Foster R, Griffin S. Foster TL, et al. Among authors: clarke d. Hepatology. 2014 Feb;59(2):408-22. doi: 10.1002/hep.26685. Epub 2013 Dec 24. Hepatology. 2014. PMID: 24022996 Free PMC article.
Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins.
Peyret H, Gehin A, Thuenemann EC, Blond D, El Turabi A, Beales L, Clarke D, Gilbert RJ, Fry EE, Stuart DI, Holmes K, Stonehouse NJ, Whelan M, Rosenberg W, Lomonossoff GP, Rowlands DJ. Peyret H, et al. Among authors: clarke d. PLoS One. 2015 Apr 1;10(4):e0120751. doi: 10.1371/journal.pone.0120751. eCollection 2015. PLoS One. 2015. PMID: 25830365 Free PMC article.
2,979 results