Clarke AR - Search Results

1

3D imaging of colorectal cancer organoids identifies responses to Tankyrase inhibitors.

Badder LM, Hollins AJ, Herpers B, Yan K, Ewan KB, Thomas M, Shone JR, Badder DA, Naven M, Ashelford KE, Hargest R, Clarke AR, Esdar C, Buchstaller HP, Treherne JM, Boj S, Ramezanpour B, Wienke D, Price LS, Shaw PH, Dale TC. Badder LM, et al. Among authors: clarke ar. PLoS One. 2020 Aug 18;15(8):e0235319. doi: 10.1371/journal.pone.0235319. eCollection 2020. PLoS One. 2020. PMID: 32810173 Free PMC article.

2

Murine models of intestinal cancer: recent advances.

Shaw P, Clarke AR. Shaw P, et al. Among authors: clarke ar. DNA Repair (Amst). 2007 Oct 1;6(10):1403-12. doi: 10.1016/j.dnarep.2007.02.022. Epub 2007 Mar 21. DNA Repair (Amst). 2007. PMID: 17376749 Review.

3

Assessment of the In Vivo Activity of PI3K and MEK Inhibitors in Genetically Defined Models of Colorectal Cancer.

Raja M, Zverev M, Seipel K, Williams GT, Clarke AR, Shaw PH. Raja M, et al. Among authors: clarke ar. Mol Cancer Ther. 2015 Oct;14(10):2175-86. doi: 10.1158/1535-7163.MCT-15-0223. Epub 2015 Jul 23. Mol Cancer Ther. 2015. PMID: 26206338

4

Deficiency of Mbd2 attenuates Wnt signaling.

Phesse TJ, Parry L, Reed KR, Ewan KB, Dale TC, Sansom OJ, Clarke AR. Phesse TJ, et al. Among authors: clarke ar. Mol Cell Biol. 2008 Oct;28(19):6094-103. doi: 10.1128/MCB.00539-08. Epub 2008 Jul 21. Mol Cell Biol. 2008. PMID: 18644872 Free PMC article.

5

In vivo and in vitro models for the therapeutic targeting of Wnt signaling using a Tet-OΔN89β-catenin system.

Jardé T, Evans RJ, McQuillan KL, Parry L, Feng GJ, Alvares B, Clarke AR, Dale TC. Jardé T, et al. Among authors: clarke ar. Oncogene. 2013 Feb 14;32(7):883-93. doi: 10.1038/onc.2012.103. Epub 2012 Apr 2. Oncogene. 2013. PMID: 22469981 Free PMC article.

6

Dual inhibition of epidermal growth factor and insulin-like 1 growth factor receptors reduce intestinal adenoma burden in the Apc(min/+) mouse.

Shaw PH, Maughan TS, Clarke AR. Shaw PH, et al. Among authors: clarke ar. Br J Cancer. 2011 Aug 23;105(5):649-57. doi: 10.1038/bjc.2011.291. Epub 2011 Aug 2. Br J Cancer. 2011. PMID: 21811251 Free PMC article.

7

Conditional disruption of Axin1 leads to development of liver tumors in mice.

Feng GJ, Cotta W, Wei XQ, Poetz O, Evans R, Jardé T, Reed K, Meniel V, Williams GT, Clarke AR, Dale TC. Feng GJ, et al. Among authors: clarke ar. Gastroenterology. 2012 Dec;143(6):1650-9. doi: 10.1053/j.gastro.2012.08.047. Epub 2012 Sep 6. Gastroenterology. 2012. PMID: 22960659

8

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

Daly CS, Shaw P, Ordonez LD, Williams GT, Quist J, Grigoriadis A, Van Es JH, Clevers H, Clarke AR, Reed KR. Daly CS, et al. Among authors: clarke ar. Oncogene. 2017 Mar 30;36(13):1793-1803. doi: 10.1038/onc.2016.342. Epub 2016 Oct 3. Oncogene. 2017. PMID: 27694902 Free PMC article.

9

Origin and maintenance of the intestinal cancer stem cell.

Davies EJ, Marsh V, Clarke AR. Davies EJ, et al. Among authors: clarke ar. Mol Carcinog. 2011 Apr;50(4):254-63. doi: 10.1002/mc.20631. Mol Carcinog. 2011. PMID: 21465575 Review.

10

Intestinal renin-angiotensin system is stimulated after deletion of Lkb1.

Shorning BY, Jardé T, McCarthy A, Ashworth A, de Leng WW, Offerhaus GJ, Resta N, Dale T, Clarke AR. Shorning BY, et al. Among authors: clarke ar. Gut. 2012 Feb;61(2):202-13. doi: 10.1136/gutjnl-2011-300046. Epub 2011 Aug 3. Gut. 2012. PMID: 21813469

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