Clark SJ - Search Results

1

Delivery Systems in Ocular Retinopathies: The Promising Future of Intravitreal Hydrogels as Sustained-Release Scaffolds.

Rafael D, Guerrero M, Marican A, Arango D, Sarmento B, Ferrer R, Durán-Lara EF, Clark SJ, Schwartz S Jr. Rafael D, et al. Among authors: clark sj. Pharmaceutics. 2023 May 12;15(5):1484. doi: 10.3390/pharmaceutics15051484. Pharmaceutics. 2023. PMID: 37242726 Free PMC article. Review.

2

Therapeutic targeting of the complement system in ocular disease.

Rathi S, Hasan R, Ueffing M, Clark SJ. Rathi S, et al. Among authors: clark sj. Drug Discov Today. 2023 Nov;28(11):103757. doi: 10.1016/j.drudis.2023.103757. Epub 2023 Aug 30. Drug Discov Today. 2023. PMID: 37657753 Free article. Review.

3

Age-related macular degeneration: A disease of extracellular complement amplification.

de Jong S, Tang J, Clark SJ. de Jong S, et al. Among authors: clark sj. Immunol Rev. 2023 Jan;313(1):279-297. doi: 10.1111/imr.13145. Epub 2022 Oct 12. Immunol Rev. 2023. PMID: 36223117 Review.

4

The complement system in age-related macular degeneration.

Armento A, Ueffing M, Clark SJ. Armento A, et al. Among authors: clark sj. Cell Mol Life Sci. 2021 May;78(10):4487-4505. doi: 10.1007/s00018-021-03796-9. Epub 2021 Mar 9. Cell Mol Life Sci. 2021. PMID: 33751148 Free PMC article. Review.

5

CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway.

Armento A, Schmidt TL, Sonntag I, Merle DA, Jarboui MA, Kilger E, Clark SJ, Ueffing M. Armento A, et al. Among authors: clark sj. Int J Mol Sci. 2021 Aug 13;22(16):8727. doi: 10.3390/ijms22168727. Int J Mol Sci. 2021. PMID: 34445430 Free PMC article.

6

FHL-1 interacts with human RPE cells through the α5β1 integrin and confers protection against oxidative stress.

Choudhury R, Bayatti N, Scharff R, Szula E, Tilakaratna V, Udsen MS, McHarg S, Askari JA, Humphries MJ, Bishop PN, Clark SJ. Choudhury R, et al. Among authors: clark sj. Sci Rep. 2021 Jul 8;11(1):14175. doi: 10.1038/s41598-021-93708-5. Sci Rep. 2021. PMID: 34239032 Free PMC article.

7

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

Merle DA, Provenzano F, Jarboui MA, Kilger E, Clark SJ, Deleidi M, Armento A, Ueffing M. Merle DA, et al. Among authors: clark sj. Antioxidants (Basel). 2021 Dec 3;10(12):1944. doi: 10.3390/antiox10121944. Antioxidants (Basel). 2021. PMID: 34943047 Free PMC article.

8

Complement Factor H Loss in RPE Cells Causes Retinal Degeneration in a Human RPE-Porcine Retinal Explant Co-Culture Model.

Armento A, Murali A, Marzi J, Almansa-Garcia AC, Arango-Gonzalez B, Kilger E, Clark SJ, Schenke-Layland K, Ramlogan-Steel CA, Steel JC, Ueffing M. Armento A, et al. Among authors: clark sj. Biomolecules. 2021 Nov 3;11(11):1621. doi: 10.3390/biom11111621. Biomolecules. 2021. PMID: 34827622 Free PMC article.

9

The eye as a complement dysregulation hotspot.

Clark SJ, Bishop PN. Clark SJ, et al. Semin Immunopathol. 2018 Jan;40(1):65-74. doi: 10.1007/s00281-017-0649-6. Epub 2017 Sep 25. Semin Immunopathol. 2018. PMID: 28948331 Free PMC article. Review.

10

Preferential production and secretion of the complement regulator factor H-like protein 1 (FHL-1) by human myeloid cells.

van Essen MF, Peereboom ETM, Schlagwein N, van Gijlswijk-Janssen DJ, Nelemans T, Joeloemsingh JV, van den Berg CW, Prins J, Clark SJ, Schmidt CQ, Trouw LA, van Kooten C. van Essen MF, et al. Among authors: clark sj. Immunobiology. 2023 May;228(3):152364. doi: 10.1016/j.imbio.2023.152364. Epub 2023 Feb 28. Immunobiology. 2023. PMID: 36881973 Free article.

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