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UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation.
Tiedemann RL, Hrit J, Du Q, Wiseman AK, Eden HE, Dickson BM, Kong X, Chomiak AA, Vaughan RM, Hebert JM, David Y, Zhou W, Baylin SB, Jones PA, Clark SJ, Rothbart SB. Tiedemann RL, et al. Among authors: clark sj. bioRxiv [Preprint]. 2024 Feb 16:2024.02.13.580169. doi: 10.1101/2024.02.13.580169. bioRxiv. 2024. PMID: 38405904 Free PMC article. Preprint.
Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma.
Meyer B, Stirzaker C, Ramkomuth S, Harvey K, Chan B, Lee CS, Karim R, Deng N, Avery-Kiejda KA, Scott RJ, Lakhani S, Fox S, Robbins E, Shin JS, Beith J, Gill A, Sioson L, Chan C, Krishnaswamy M, Cooper C, Warrier S, Mak C, Rasko JE, Bailey CG, Swarbrick A, Clark SJ, O'Toole S, Pidsley R. Meyer B, et al. Among authors: clark sj. J Pathol. 2024 Apr;262(4):480-494. doi: 10.1002/path.6250. Epub 2024 Feb 1. J Pathol. 2024. PMID: 38300122
The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer.
Achinger-Kawecka J, Stirzaker C, Portman N, Campbell E, Chia KM, Du Q, Laven-Law G, Nair SS, Yong A, Wilkinson A, Clifton S, Milioli HH, Alexandrou S, Caldon CE, Song J, Khoury A, Meyer B, Chen W, Pidsley R, Qu W, Gee JMW, Schmitt A, Wong ES, Hickey TE, Lim E, Clark SJ. Achinger-Kawecka J, et al. Among authors: clark sj. Nat Struct Mol Biol. 2024 Mar;31(3):498-512. doi: 10.1038/s41594-023-01181-7. Epub 2024 Jan 5. Nat Struct Mol Biol. 2024. PMID: 38182927 Free PMC article.
801 results