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Spore-FP1 tuberculosis mucosal vaccine candidate is highly protective in guinea pigs but fails to improve on BCG-conferred protection in non-human primates.
White AD, Tran AC, Sibley L, Sarfas C, Morrison AL, Lawrence S, Dennis M, Clark S, Zadi S, Lanni F, Rayner E, Copland A, Hart P, Diogo GR, Paul MJ, Kim M, Gleeson F, Salguero FJ, Singh M, Stehr M, Cutting SM, Basile JI, Rottenberg ME, Williams A, Sharpe SA, Reljic R. White AD, et al. Among authors: clark s. Front Immunol. 2023 Oct 10;14:1246826. doi: 10.3389/fimmu.2023.1246826. eCollection 2023. Front Immunol. 2023. PMID: 37881438 Free PMC article.
Animal models of tuberculosis: Guinea pigs.
Clark S, Hall Y, Williams A. Clark S, et al. Cold Spring Harb Perspect Med. 2014 Dec 18;5(5):a018572. doi: 10.1101/cshperspect.a018572. Cold Spring Harb Perspect Med. 2014. PMID: 25524720 Free PMC article. Review.
Alternative BCG delivery strategies improve protection against Mycobacterium tuberculosis in non-human primates: Protection associated with mycobacterial antigen-specific CD4 effector memory T-cell populations.
Sharpe S, White A, Sarfas C, Sibley L, Gleeson F, McIntyre A, Basaraba R, Clark S, Hall G, Rayner E, Williams A, Marsh PD, Dennis M. Sharpe S, et al. Among authors: clark s. Tuberculosis (Edinb). 2016 Dec;101:174-190. doi: 10.1016/j.tube.2016.09.004. Epub 2016 Oct 8. Tuberculosis (Edinb). 2016. PMID: 27865390 Free PMC article.
Establishment of an aerosol challenge model of tuberculosis in rhesus macaques and an evaluation of endpoints for vaccine testing.
Sharpe SA, McShane H, Dennis MJ, Basaraba RJ, Gleeson F, Hall G, McIntyre A, Gooch K, Clark S, Beveridge NE, Nuth E, White A, Marriott A, Dowall S, Hill AV, Williams A, Marsh PD. Sharpe SA, et al. Among authors: clark s. Clin Vaccine Immunol. 2010 Aug;17(8):1170-82. doi: 10.1128/CVI.00079-10. Epub 2010 Jun 9. Clin Vaccine Immunol. 2010. PMID: 20534795 Free PMC article.
Route of delivery to the airway influences the distribution of pulmonary disease but not the outcome of Mycobacterium tuberculosis infection in rhesus macaques.
Sibley L, Dennis M, Sarfas C, White A, Clark S, Gleeson F, McIntyre A, Rayner E, Pearson G, Williams A, Marsh P, Sharpe S. Sibley L, et al. Among authors: clark s. Tuberculosis (Edinb). 2016 Jan;96:141-9. doi: 10.1016/j.tube.2015.11.004. Epub 2015 Nov 30. Tuberculosis (Edinb). 2016. PMID: 26723465 Free article.
5,128 results