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Single-cell multi-omic analysis profiles defective genome activation and epigenetic reprogramming associated with human pre-implantation embryo arrest.
Hernandez Mora JR, Buhigas C, Clark S, Del Gallego Bonilla R, Daskeviciute D, Monteagudo-Sánchez A, Poo-Llanillo ME, Medrano JV, Simón C, Meseguer M, Kelsey G, Monk D. Hernandez Mora JR, et al. Among authors: clark s. Cell Rep. 2023 Feb 28;42(2):112100. doi: 10.1016/j.celrep.2023.112100. Epub 2023 Feb 9. Cell Rep. 2023. PMID: 36763500 Free article.
Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis.
Nashun B, Hill PW, Smallwood SA, Dharmalingam G, Amouroux R, Clark SJ, Sharma V, Ndjetehe E, Pelczar P, Festenstein RJ, Kelsey G, Hajkova P. Nashun B, et al. Among authors: clark sj. Mol Cell. 2015 Nov 19;60(4):611-25. doi: 10.1016/j.molcel.2015.10.010. Epub 2015 Nov 5. Mol Cell. 2015. PMID: 26549683 Free PMC article.
Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.
Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W. Angermueller C, et al. Among authors: clark sj. Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11. Nat Methods. 2016. PMID: 26752769 Free PMC article.
Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.
Rulands S, Lee HJ, Clark SJ, Angermueller C, Smallwood SA, Krueger F, Mohammed H, Dean W, Nichols J, Rugg-Gunn P, Kelsey G, Stegle O, Simons BD, Reik W. Rulands S, et al. Among authors: clark sj. Cell Syst. 2018 Jul 25;7(1):63-76.e12. doi: 10.1016/j.cels.2018.06.012. Cell Syst. 2018. PMID: 30031774 Free PMC article.
Multi-omics profiling of mouse gastrulation at single-cell resolution.
Argelaguet R, Clark SJ, Mohammed H, Stapel LC, Krueger C, Kapourani CA, Imaz-Rosshandler I, Lohoff T, Xiang Y, Hanna CW, Smallwood S, Ibarra-Soria X, Buettner F, Sanguinetti G, Xie W, Krueger F, Göttgens B, Rugg-Gunn PJ, Kelsey G, Dean W, Nichols J, Stegle O, Marioni JC, Reik W. Argelaguet R, et al. Among authors: clark sj. Nature. 2019 Dec;576(7787):487-491. doi: 10.1038/s41586-019-1825-8. Epub 2019 Dec 11. Nature. 2019. PMID: 31827285 Free PMC article.
The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances.
Monteagudo-Sánchez A, Hernandez Mora JR, Simon C, Burton A, Tenorio J, Lapunzina P, Clark S, Esteller M, Kelsey G, López-Siguero JP, de Nanclares GP, Torres-Padilla ME, Monk D. Monteagudo-Sánchez A, et al. Among authors: clark s. Nucleic Acids Res. 2020 Nov 18;48(20):11394-11407. doi: 10.1093/nar/gkaa837. Nucleic Acids Res. 2020. PMID: 33053156 Free PMC article.
5,128 results