Clark J - Search Results

1

NAD⁺ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.

Li J, M Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, Beiser A, Andrews JF, Sun M, Koczor CA, Clark J, Hayat F, Makarov MV, Wilk A, Yates NA, Migaud ME, Sobol RW. Li J, et al. Among authors: clark j. NAR Cancer. 2021 Nov 17;3(4):zcab044. doi: 10.1093/narcan/zcab044. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34806016 Free PMC article.

2

UBE3B Is a Calmodulin-regulated, Mitochondrion-associated E3 Ubiquitin Ligase.

Braganza A, Li J, Zeng X, Yates NA, Dey NB, Andrews J, Clark J, Zamani L, Wang XH, St Croix C, O'Sullivan R, Garcia-Exposito L, Brodsky JL, Sobol RW. Braganza A, et al. Among authors: clark j. J Biol Chem. 2017 Feb 10;292(6):2470-2484. doi: 10.1074/jbc.M116.766824. Epub 2016 Dec 21. J Biol Chem. 2017. PMID: 28003368 Free PMC article.

3

EGFR Mutations Compromise Hypoxia-Associated Radiation Resistance through Impaired Replication Fork-Associated DNA Damage Repair.

Saki M, Makino H, Javvadi P, Tomimatsu N, Ding LH, Clark JE, Gavin E, Takeda K, Andrews J, Saha D, Story MD, Burma S, Nirodi CS. Saki M, et al. Among authors: clark je. Mol Cancer Res. 2017 Nov;15(11):1503-1516. doi: 10.1158/1541-7786.MCR-17-0136. Epub 2017 Aug 11. Mol Cancer Res. 2017. PMID: 28801308 Free PMC article.

4

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.

Fang Q, Andrews J, Sharma N, Wilk A, Clark J, Slyskova J, Koczor CA, Lans H, Prakash A, Sobol RW. Fang Q, et al. Among authors: clark j. Nucleic Acids Res. 2019 Jul 9;47(12):6269-6286. doi: 10.1093/nar/gkz293. Nucleic Acids Res. 2019. PMID: 31287140 Free PMC article.

5

Extracellular NAD⁺ enhances PARP-dependent DNA repair capacity independently of CD73 activity.

Wilk A, Hayat F, Cunningham R, Li J, Garavaglia S, Zamani L, Ferraris DM, Sykora P, Andrews J, Clark J, Davis A, Chaloin L, Rizzi M, Migaud M, Sobol RW. Wilk A, et al. Among authors: clark j. Sci Rep. 2020 Jan 20;10(1):651. doi: 10.1038/s41598-020-57506-9. Sci Rep. 2020. PMID: 31959836 Free PMC article.

6

NAD⁺-mediated regulation of mammalian base excision repair.

Saville KM, Clark J, Wilk A, Rogers GD, Andrews JF, Koczor CA, Sobol RW. Saville KM, et al. Among authors: clark j. DNA Repair (Amst). 2020 Sep;93:102930. doi: 10.1016/j.dnarep.2020.102930. DNA Repair (Amst). 2020. PMID: 33087267 Free PMC article. Review.

7

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD⁺/SIRT6 axis.

Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW. Koczor CA, et al. Among authors: clark j. Cell Rep. 2021 Nov 2;37(5):109917. doi: 10.1016/j.celrep.2021.109917. Cell Rep. 2021. PMID: 34731617 Free PMC article.

8

A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1.

Das D, Duncton MAJ, Georgiadis TM, Pellicena P, Clark J, Sobol RW, Georgiadis MM, King-Underwood J, Jobes DV, Chang C, Gao Y, Deacon AM, Wilson DM 3rd. Das D, et al. Among authors: clark j. Int J Mol Sci. 2023 Nov 23;24(23):16637. doi: 10.3390/ijms242316637. Int J Mol Sci. 2023. PMID: 38068959 Free PMC article.

9

TRIP12 governs DNA Polymerase β involvement in DNA damage response and repair.

Inanc B, Fang Q, Andrews JF, Zeng X, Clark J, Li J, Dey NB, Ibrahim M, Sykora P, Yu Z, Braganza A, Verheij M, Jonkers J, Yates NA, Vens C, Sobol RW. Inanc B, et al. Among authors: clark j. bioRxiv [Preprint]. 2024 Apr 10:2024.04.08.588474. doi: 10.1101/2024.04.08.588474. bioRxiv. 2024. PMID: 38645048 Free PMC article. Preprint.

10

Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium.

Clark J, Alvarez DF, Alexeyev M, King JA, Huang L, Yoder MC, Stevens T. Clark J, et al. Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L431-9. doi: 10.1152/ajplung.00316.2007. Epub 2007 Nov 2. Am J Physiol Lung Cell Mol Physiol. 2008. PMID: 17981956 Free article.

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