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Truncation of ADAMTS13 by Plasmin Enhances Its Activity in Plasma.
Clark CC, Mebius MM, de Maat S, Tielens AGM, de Groot PG, Urbanus RT, Fijnheer R, Hazenberg BPC, van Hellemond JJ, Maas C. Clark CC, et al. Thromb Haemost. 2018 Mar;118(3):471-479. doi: 10.1055/s-0038-1627460. Epub 2018 Mar 13. Thromb Haemost. 2018. PMID: 29534248
Factor XII truncation accelerates activation in solution.
de Maat S, Clark CC, Boertien M, Parr N, Sanrattana W, Hofman ZLM, Maas C. de Maat S, et al. Among authors: clark cc. J Thromb Haemost. 2019 Jan;17(1):183-194. doi: 10.1111/jth.14325. Epub 2018 Dec 10. J Thromb Haemost. 2019. PMID: 30394658 Free PMC article.
A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation.
Hofman ZLM, Clark CC, Sanrattana W, Nosairi A, Parr NMJ, Živkovic M, Krause K, Mahnke NA, Scheffel J, Hack CE, Maurer M, de Maat S, Maas C. Hofman ZLM, et al. Among authors: clark cc. J Biol Chem. 2020 Jan 10;295(2):363-374. doi: 10.1074/jbc.RA119.009788. Epub 2019 Nov 26. J Biol Chem. 2020. PMID: 31771982 Free PMC article.
Thrombotic Events in COVID-19 Are Associated With a Lower Use of Prophylactic Anticoagulation Before Hospitalization and Followed by Decreases in Platelet Reactivity.
Clark CC, Jukema BN, Barendrecht AD, Spanjaard JS, Jorritsma NKN, Smits S, de Maat S, Seinen CW, Verhoef S, Parr NMJ, Sebastian SAE, Koekman AC, van Wesel ACW, van Goor HMR, Spijkerman R, Bongers SH, van der Vries E, Nierkens S, Boes M, Koenderman L, Kaasjager KAH, Maas C. Clark CC, et al. Front Med (Lausanne). 2021 Apr 22;8:650129. doi: 10.3389/fmed.2021.650129. eCollection 2021. Front Med (Lausanne). 2021. PMID: 33968958 Free PMC article.
Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis.
de Maat S, Clark CC, Barendrecht AD, Smits S, van Kleef ND, El Otmani H, Waning M, van Moorsel M, Szardenings M, Delaroque N, Vercruysse K, Urbanus RT, Sebastian S, Lenting PJ, Hagemeyer CE, Renné T, Vanhoorelbeke K, Tersteeg C, Maas C. de Maat S, et al. Among authors: clark cc. Blood. 2022 Jan 27;139(4):597-607. doi: 10.1182/blood.2021011776. Blood. 2022. PMID: 34752601 Free article.
483 results