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Discovery of a "true" aspirin prodrug.
Moriarty LM, Lally MN, Carolan CG, Jones M, Clancy JM, Gilmer JF. Moriarty LM, et al. Among authors: clancy jm. J Med Chem. 2008 Dec 25;51(24):7991-9. doi: 10.1021/jm801094c. J Med Chem. 2008. PMID: 19049433
Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups.
Jones M, Inkielewicz I, Medina C, Santos-Martinez MJ, Radomski A, Radomski MW, Lally MN, Moriarty LM, Gaynor J, Carolan CG, Khan D, O'Byrne P, Harmon S, Holland V, Clancy JM, Gilmer JF. Jones M, et al. Among authors: clancy jm. J Med Chem. 2009 Nov 12;52(21):6588-98. doi: 10.1021/jm900561s. J Med Chem. 2009. PMID: 19821574
Beta-aminoketones as prodrugs with pH-controlled activation.
Simplício AL, Clancy JM, Gilmer JF. Simplício AL, et al. Among authors: clancy jm. Int J Pharm. 2007 May 24;336(2):208-14. doi: 10.1016/j.ijpharm.2006.11.055. Epub 2006 Dec 1. Int J Pharm. 2007. PMID: 17197138
35 results