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Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism.
Gritti I, Basso V, Rinchai D, Corigliano F, Pivetti S, Gaviraghi M, Rosano D, Mazza D, Barozzi S, Roncador M, Parmigiani G, Legube G, Parazzoli D, Cittaro D, Bedognetti D, Mondino A, Segalla S, Tonon G. Gritti I, et al. Among authors: cittaro d. EMBO J. 2022 Nov 17;41(22):e108040. doi: 10.15252/embj.2021108040. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215697 Free PMC article.
Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation.
Fumagalli M, Rossiello F, Clerici M, Barozzi S, Cittaro D, Kaplunov JM, Bucci G, Dobreva M, Matti V, Beausejour CM, Herbig U, Longhese MP, d'Adda di Fagagna F. Fumagalli M, et al. Among authors: d adda di fagagna f, cittaro d. Nat Cell Biol. 2012 Mar 18;14(4):355-65. doi: 10.1038/ncb2466. Nat Cell Biol. 2012. PMID: 22426077 Free PMC article.
Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.
Rondinelli B, Rosano D, Antonini E, Frenquelli M, Montanini L, Huang D, Segalla S, Yoshihara K, Amin SB, Lazarevic D, The BT, Verhaak RG, Futreal PA, Di Croce L, Chin L, Cittaro D, Tonon G. Rondinelli B, et al. Among authors: cittaro d. J Clin Invest. 2015 Dec;125(12):4625-37. doi: 10.1172/JCI81040. Epub 2015 Nov 9. J Clin Invest. 2015. PMID: 26551685 Free PMC article.
Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene.
Santoliquido BM, Frenquelli M, Contadini C, Bestetti S, Gaviraghi M, Barbieri E, De Antoni A, Albarello L, Amabile A, Gardini A, Lombardo A, Doglioni C, Provero P, Soddu S, Cittaro D, Tonon G. Santoliquido BM, et al. Among authors: cittaro d. Life Sci Alliance. 2021 Jun 29;4(8):e202101019. doi: 10.26508/lsa.202101019. Print 2021 Aug. Life Sci Alliance. 2021. PMID: 34187875 Free PMC article.
Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin.
Tedesco M, Giannese F, Lazarević D, Giansanti V, Rosano D, Monzani S, Catalano I, Grassi E, Zanella ER, Botrugno OA, Morelli L, Panina Bordignon P, Caravagna G, Bertotti A, Martino G, Aldrighetti L, Pasqualato S, Trusolino L, Cittaro D, Tonon G. Tedesco M, et al. Among authors: cittaro d. Nat Biotechnol. 2022 Feb;40(2):235-244. doi: 10.1038/s41587-021-01031-1. Epub 2021 Oct 11. Nat Biotechnol. 2022. PMID: 34635836
Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer.
Rondinelli B, Rosano D, Antonini E, Frenquelli M, Montanini L, Huang D, Segalla S, Yoshihara K, Amin SB, Lazarevic D, The BT, Verhaak RG, Futreal PA, Di Croce L, Chin L, Cittaro D, Tonon G. Rondinelli B, et al. Among authors: cittaro d. J Clin Invest. 2016 Nov 1;126(11):4387. doi: 10.1172/JCI91191. Epub 2016 Nov 1. J Clin Invest. 2016. PMID: 27801678 Free PMC article. No abstract available.
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