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Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum.
Santos MF, Rappa G, Karbanová J, Fontana S, Bella MAD, Pope MR, Parrino B, Cascioferro SM, Vistoli G, Diana P, Cirrincione G, Arena GO, Woo G, Huang K, Huynh T, Moschetti M, Alessandro R, Corbeil D, Lorico A. Santos MF, et al. Among authors: cirrincione g. J Extracell Vesicles. 2021 Aug;10(10):e12132. doi: 10.1002/jev2.12132. Epub 2021 Aug 14. J Extracell Vesicles. 2021. PMID: 34429859 Free PMC article.
Discovery of the 3-Amino-1,2,4-triazine-Based Library as Selective PDK1 Inhibitors with Therapeutic Potential in Highly Aggressive Pancreatic Ductal Adenocarcinoma.
Carbone D, De Franco M, Pecoraro C, Bassani D, Pavan M, Cascioferro S, Parrino B, Cirrincione G, Dall'Acqua S, Moro S, Gandin V, Diana P. Carbone D, et al. Among authors: cirrincione g. Int J Mol Sci. 2023 Feb 12;24(4):3679. doi: 10.3390/ijms24043679. Int J Mol Sci. 2023. PMID: 36835086 Free PMC article.
Structural Manipulations of Marine Natural Products Inspire a New Library of 3-Amino-1,2,4-Triazine PDK Inhibitors Endowed with Antitumor Activity in Pancreatic Ductal Adenocarcinoma.
Carbone D, De Franco M, Pecoraro C, Bassani D, Pavan M, Cascioferro S, Parrino B, Cirrincione G, Dall'Acqua S, Sut S, Moro S, Gandin V, Diana P. Carbone D, et al. Among authors: cirrincione g. Mar Drugs. 2023 May 4;21(5):288. doi: 10.3390/md21050288. Mar Drugs. 2023. PMID: 37233482 Free PMC article.
Biological Evaluation of the Antiproliferative and Anti-migratory Activity of a Series of 3-(6-Phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-1H-indole Derivatives Against Pancreatic Cancer Cells.
Li Petri G, Cascioferro S, El Hassouni B, Carbone D, Parrino B, Cirrincione G, Peters GJ, Diana P, Giovannetti E. Li Petri G, et al. Among authors: cirrincione g. Anticancer Res. 2019 Jul;39(7):3615-3620. doi: 10.21873/anticanres.13509. Anticancer Res. 2019. PMID: 31262887
119 results