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A Therapeutically Actionable Protumoral Axis of Cytokines Involving IL-8, TNFα, and IL-1β.
Olivera I, Sanz-Pamplona R, Bolaños E, Rodriguez I, Etxeberria I, Cirella A, Egea J, Garasa S, Migueliz I, Eguren-Santamaria I, Sanmamed MF, Glez-Vaz J, Azpilikueta A, Alvarez M, Ochoa MC, Malacrida B, Propper D, de Andrea CE, Berraondo P, Balkwill FR, Teijeira Á, Melero I. Olivera I, et al. Among authors: cirella a. Cancer Discov. 2022 Sep 2;12(9):2140-2157. doi: 10.1158/2159-8290.CD-21-1115. Cancer Discov. 2022. PMID: 35771565
CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity.
Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I. Teijeira Á, et al. Among authors: cirella a. Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13. Immunity. 2020. PMID: 32289253 Free article.
Interleukin-12 Message in a Bottle.
Cirella A, Berraondo P, Di Trani CA, Melero I. Cirella A, et al. Clin Cancer Res. 2020 Dec 1;26(23):6080-6082. doi: 10.1158/1078-0432.CCR-20-3250. Epub 2020 Oct 1. Clin Cancer Res. 2020. PMID: 33004432
IL8, Neutrophils, and NETs in a Collusion against Cancer Immunity and Immunotherapy.
Teijeira A, Garasa S, Ochoa MC, Villalba M, Olivera I, Cirella A, Eguren-Santamaria I, Berraondo P, Schalper KA, de Andrea CE, Sanmamed MF, Melero I. Teijeira A, et al. Among authors: cirella a. Clin Cancer Res. 2021 May 1;27(9):2383-2393. doi: 10.1158/1078-0432.CCR-20-1319. Epub 2020 Dec 29. Clin Cancer Res. 2021. PMID: 33376096 Review.
Mouse Models of Peritoneal Carcinomatosis to Develop Clinical Applications.
Bella Á, Di Trani CA, Fernández-Sendin M, Arrizabalaga L, Cirella A, Teijeira Á, Medina-Echeverz J, Melero I, Berraondo P, Aranda F. Bella Á, et al. Among authors: cirella a. Cancers (Basel). 2021 Feb 25;13(5):963. doi: 10.3390/cancers13050963. Cancers (Basel). 2021. PMID: 33669017 Free PMC article. Review.
Differential Interleukin-8 thresholds for chemotaxis and netosis in human neutrophils.
Teijeira A, Garasa S, Ochoa MDC, Cirella A, Olivera I, Glez-Vaz J, Andueza MP, Migueliz I, Alvarez M, Rodríguez-Ruiz ME, Rouzaut A, Berraondo P, Sanmamed MF, Perez Gracia JL, Melero I. Teijeira A, et al. Among authors: cirella a. Eur J Immunol. 2021 Sep;51(9):2274-2280. doi: 10.1002/eji.202049029. Epub 2021 Jun 4. Eur J Immunol. 2021. PMID: 33963542 Free article.
Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Etxeberria I, Bolaños E, Teijeira A, Garasa S, Yanguas A, Azpilikueta A, Kavanaugh WM, Vasiljeva O, Belvin M, Howng B, Irving B, Tipton K, West J, Mei L, Korman AJ, Sega E, Olivera I, Cirella A, Ochoa MC, Rodriguez ME, Melero A, Sanmamed MF, Engelhardt JJ, Melero I. Etxeberria I, et al. Among authors: cirella a. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2025930118. doi: 10.1073/pnas.2025930118. Proc Natl Acad Sci U S A. 2021. PMID: 34172583 Free PMC article.
Advances in mRNA-based drug discovery in cancer immunotherapy.
Di Trani CA, Fernandez-Sendin M, Cirella A, Segués A, Olivera I, Bolaños E, Melero I, Berraondo P. Di Trani CA, et al. Among authors: cirella a. Expert Opin Drug Discov. 2022 Jan;17(1):41-53. doi: 10.1080/17460441.2021.1978972. Epub 2021 Sep 20. Expert Opin Drug Discov. 2022. PMID: 34496689 Review.
Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies.
Glez-Vaz J, Azpilikueta A, Olivera I, Cirella A, Teijeira A, Ochoa MC, Alvarez M, Eguren-Santamaria I, Luri-Rey C, Rodriguez-Ruiz ME, Nie X, Chen L, Guedan S, Sanamed MF, Perez Gracia JL, Melero I. Glez-Vaz J, et al. Among authors: cirella a. J Immunother Cancer. 2022 Mar;10(3):e003532. doi: 10.1136/jitc-2021-003532. J Immunother Cancer. 2022. PMID: 35236742 Free PMC article.
Novel strategies exploiting interleukin-12 in cancer immunotherapy.
Cirella A, Luri-Rey C, Di Trani CA, Teijeira A, Olivera I, Bolaños E, Castañón E, Palencia B, Brocco D, Fernández-Sendin M, Aranda F, Berraondo P, Melero I. Cirella A, et al. Pharmacol Ther. 2022 Nov;239:108189. doi: 10.1016/j.pharmthera.2022.108189. Epub 2022 Apr 14. Pharmacol Ther. 2022. PMID: 35430292 Review.
34 results