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Involvement of Phosphodiesterase 2A Activity in the Pathophysiology of Fragile X Syndrome.
Maurin T, Melancia F, Jarjat M, Castro L, Costa L, Delhaye S, Khayachi A, Castagnola S, Mota E, Di Giorgio A, Servadio M, Drozd M, Poupon G, Schiavi S, Sardone L, Azoulay S, Ciranna L, Martin S, Vincent P, Trezza V, Bardoni B. Maurin T, et al. Among authors: ciranna l. Cereb Cortex. 2019 Jul 22;29(8):3241-3252. doi: 10.1093/cercor/bhy192. Cereb Cortex. 2019. PMID: 30137253
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
Costa L, Spatuzza M, D'Antoni S, Bonaccorso CM, Trovato C, Musumeci SA, Leopoldo M, Lacivita E, Catania MV, Ciranna L. Costa L, et al. Among authors: ciranna l. Biol Psychiatry. 2012 Dec 1;72(11):924-33. doi: 10.1016/j.biopsych.2012.06.008. Epub 2012 Jul 18. Biol Psychiatry. 2012. PMID: 22817866
A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine.
Pecoraro V, Sardone LM, Chisari M, Licata F, Li Volsi G, Perciavalle V, Ciranna L, Costa L. Pecoraro V, et al. Among authors: ciranna l. Neuroscience. 2017 Jan 6;340:551-562. doi: 10.1016/j.neuroscience.2016.10.061. Epub 2016 Nov 2. Neuroscience. 2017. PMID: 27816700
Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice.
Aloisi E, Le Corf K, Dupuis J, Zhang P, Ginger M, Labrousse V, Spatuzza M, Georg Haberl M, Costa L, Shigemoto R, Tappe-Theodor A, Drago F, Vincenzo Piazza P, Mulle C, Groc L, Ciranna L, Catania MV, Frick A. Aloisi E, et al. Among authors: ciranna l. Nat Commun. 2017 Oct 24;8(1):1103. doi: 10.1038/s41467-017-01191-2. Nat Commun. 2017. PMID: 29062097 Free PMC article.
Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome.
Costa L, Sardone LM, Bonaccorso CM, D'Antoni S, Spatuzza M, Gulisano W, Tropea MR, Puzzo D, Leopoldo M, Lacivita E, Catania MV, Ciranna L. Costa L, et al. Among authors: ciranna l. Front Mol Neurosci. 2018 Oct 2;11:353. doi: 10.3389/fnmol.2018.00353. eCollection 2018. Front Mol Neurosci. 2018. PMID: 30333723 Free PMC article.
46 results