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First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development.
Jonas O, Calligaris D, Methuku KR, Poe MM, Francois JP, Tranghese F, Changelian A, Sieghart W, Ernst M, Krummel DA, Cook JM, Pomeroy SL, Cima M, Agar NY, Langer R, Sengupta S. Jonas O, et al. Among authors: cima m. J Biomed Nanotechnol. 2016 Jun;12(6):1297-302. doi: 10.1166/jbn.2016.2262. J Biomed Nanotechnol. 2016. PMID: 27319222 Free PMC article.
Microchip technology in drug delivery.
Santini JT Jr, Richards AC, Scheidt RA, Cima MJ, Langer RS. Santini JT Jr, et al. Among authors: cima mj. Ann Med. 2000 Sep;32(6):377-9. doi: 10.3109/07853890008995941. Ann Med. 2000. PMID: 11028682
In vivo release from a drug delivery MEMS device.
Li Y, Shawgo RS, Tyler B, Henderson PT, Vogel JS, Rosenberg A, Storm PB, Langer R, Brem H, Cima MJ. Li Y, et al. J Control Release. 2004 Nov 24;100(2):211-9. doi: 10.1016/j.jconrel.2004.08.018. J Control Release. 2004. PMID: 15544869
In vivo delivery of BCNU from a MEMS device to a tumor model.
Li Y, Ho Duc HL, Tyler B, Williams T, Tupper M, Langer R, Brem H, Cima MJ. Li Y, et al. Among authors: cima mj. J Control Release. 2005 Aug 18;106(1-2):138-45. doi: 10.1016/j.jconrel.2005.04.009. J Control Release. 2005. PMID: 16167384
Implantable diagnostic device for cancer monitoring.
Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ. Daniel KD, et al. Among authors: cima mj. Biosens Bioelectron. 2009 Jul 15;24(11):3252-7. doi: 10.1016/j.bios.2009.04.010. Epub 2009 Apr 16. Biosens Bioelectron. 2009. PMID: 19442510 Free PMC article.
First-in-human testing of a wirelessly controlled drug delivery microchip.
Farra R, Sheppard NF Jr, McCabe L, Neer RM, Anderson JM, Santini JT Jr, Cima MJ, Langer R. Farra R, et al. Among authors: cima mj. Sci Transl Med. 2012 Feb 22;4(122):122ra21. doi: 10.1126/scitranslmed.3003276. Epub 2012 Feb 16. Sci Transl Med. 2012. PMID: 22344516 Clinical Trial.
181 results