Cilliers C - Search Results

1

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle.

Bartelink IH, Jones EF, Shahidi-Latham SK, Lee PRE, Zheng Y, Vicini P, van 't Veer L, Wolf D, Iagaru A, Kroetz DL, Prideaux B, Cilliers C, Thurber GM, Wimana Z, Gebhart G. Bartelink IH, et al. Among authors: cilliers c. Clin Pharmacol Ther. 2019 Jul;106(1):148-163. doi: 10.1002/cpt.1211. Epub 2018 Oct 6. Clin Pharmacol Ther. 2019. PMID: 30107040 Free PMC article. Review.

2

Multiscale Modeling of Antibody-Drug Conjugates: Connecting Tissue and Cellular Distribution to Whole Animal Pharmacokinetics and Potential Implications for Efficacy.

Cilliers C, Guo H, Liao J, Christodolu N, Thurber GM. Cilliers C, et al. AAPS J. 2016 Sep;18(5):1117-1130. doi: 10.1208/s12248-016-9940-z. Epub 2016 Jun 10. AAPS J. 2016. PMID: 27287046 Free PMC article.

3

An Agent-Based Systems Pharmacology Model of the Antibody-Drug Conjugate Kadcyla to Predict Efficacy of Different Dosing Regimens.

Menezes B, Cilliers C, Wessler T, Thurber GM, Linderman JJ. Menezes B, et al. Among authors: cilliers c. AAPS J. 2020 Jan 15;22(2):29. doi: 10.1208/s12248-019-0391-1. AAPS J. 2020. PMID: 31942650 Free PMC article.

4

Multichannel imaging to quantify four classes of pharmacokinetic distribution in tumors.

Bhatnagar S, Deschenes E, Liao J, Cilliers C, Thurber GM. Bhatnagar S, et al. Among authors: cilliers c. J Pharm Sci. 2014 Oct;103(10):3276-86. doi: 10.1002/jps.24086. Epub 2014 Jul 21. J Pharm Sci. 2014. PMID: 25048378 Free PMC article.

5

Improved Tumor Penetration and Single-Cell Targeting of Antibody-Drug Conjugates Increases Anticancer Efficacy and Host Survival.

Cilliers C, Menezes B, Nessler I, Linderman J, Thurber GM. Cilliers C, et al. Cancer Res. 2018 Feb 1;78(3):758-768. doi: 10.1158/0008-5472.CAN-17-1638. Epub 2017 Dec 7. Cancer Res. 2018. PMID: 29217763 Free PMC article.

6

"Standing by" for Bystander Effects: Dual-Isotope Imaging of Antibody-Drug Conjugate and Payload Distribution.

Cilliers C, Thurber GM. Cilliers C, et al. J Nucl Med. 2018 Sep;59(9):1459-1460. doi: 10.2967/jnumed.118.213389. Epub 2018 Jul 12. J Nucl Med. 2018. PMID: 30002110 Free article. No abstract available.

7

Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging.

Nessler I, Cilliers C, Thurber GM. Nessler I, et al. Among authors: cilliers c. Pharmaceutics. 2020 Feb 5;12(2):132. doi: 10.3390/pharmaceutics12020132. Pharmaceutics. 2020. PMID: 32033318 Free PMC article.

8

Tracking Antibody Distribution with Near-Infrared Fluorescent Dyes: Impact of Dye Structure and Degree of Labeling on Plasma Clearance.

Cilliers C, Nessler I, Christodolu N, Thurber GM. Cilliers C, et al. Mol Pharm. 2017 May 1;14(5):1623-1633. doi: 10.1021/acs.molpharmaceut.6b01091. Epub 2017 Mar 31. Mol Pharm. 2017. PMID: 28294622 Free PMC article.

9

Pharmacokinetics and Pharmacodynamics of TAK-164 Antibody Drug Conjugate Coadministered with Unconjugated Antibody.

Menezes B, Khera E, Calopiz M, Smith MD, Ganno ML, Cilliers C, Abu-Yousif AO, Linderman JJ, Thurber GM. Menezes B, et al. Among authors: cilliers c. AAPS J. 2022 Oct 7;24(6):107. doi: 10.1208/s12248-022-00756-4. AAPS J. 2022. PMID: 36207468 Free PMC article.

10

Residualization Rates of Near-Infrared Dyes for the Rational Design of Molecular Imaging Agents.

Cilliers C, Liao J, Atangcho L, Thurber GM. Cilliers C, et al. Mol Imaging Biol. 2015 Dec;17(6):757-62. doi: 10.1007/s11307-015-0851-7. Mol Imaging Biol. 2015. PMID: 25869081 Free PMC article.

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