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Avoiding Drug Resistance in HIV Reverse Transcriptase.
Chem Rev. 2021 Mar 24;121(6):3271-3296. doi: 10.1021/acs.chemrev.0c00967. Epub 2021 Jan 28.
Chem Rev. 2021.
PMID: 33507067
Free PMC article.
Review.
Development of Human Immunodeficiency Virus Type 1 Resistance to 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine Starting with Wild-Type or Nucleoside Reverse Transcriptase Inhibitor-Resistant Strains.
Cilento ME, Reeve AB, Michailidis E, Ilina TV, Nagy E, Mitsuya H, Parniak MA, Tedbury PR, Sarafianos SG.
Cilento ME, et al.
Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0116721. doi: 10.1128/AAC.01167-21. Epub 2021 Sep 13.
Antimicrob Agents Chemother. 2021.
PMID: 34516245
Free PMC article.
Clinical Trial.
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Potency and metabolic stability: a molecular hybrid case in the design of novel PF74-like small molecules targeting HIV-1 capsid protein.
Sahani RL, Akther T, Cilento ME, Castaner AE, Zhang H, Kirby KA, Xie J, Sarafianos SG, Wang Z.
Sahani RL, et al. Among authors: cilento me.
RSC Med Chem. 2021 Sep 28;12(12):2031-2044. doi: 10.1039/d1md00292a. eCollection 2021 Dec 15.
RSC Med Chem. 2021.
PMID: 35028563
Free PMC article.
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Drug Interactions in Lenacapavir-Based Long-Acting Antiviral Combinations.
Cilento ME, Ong YT, Tedbury PR, Sarafianos SG.
Cilento ME, et al.
Viruses. 2022 May 31;14(6):1202. doi: 10.3390/v14061202.
Viruses. 2022.
PMID: 35746673
Free PMC article.
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Nirmatrelvir Resistance in SARS-CoV-2 Omicron_BA.1 and WA1 Replicons and Escape Strategies.
Lan S, Neilsen G, Slack RL, Cantara WA, Castaner AE, Lorson ZC, Lulkin N, Zhang H, Lee J, Cilento ME, Tedbury PR, Sarafianos SG.
Lan S, et al. Among authors: cilento me.
bioRxiv [Preprint]. 2023 Jan 3:2022.12.31.522389. doi: 10.1101/2022.12.31.522389.
bioRxiv. 2023.
PMID: 36656782
Free PMC article.
Preprint.
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HIV-1 Resistance to Islatravir/Tenofovir Combination Therapy in Wild-Type or NRTI-Resistant Strains of Diverse HIV-1 Subtypes.
Cilento ME, Wen X, Reeve AB, Ukah OB, Snyder AA, Carrillo CM, Smith CP, Edwards K, Wahoski CC, Kitzler DR, Kodama EN, Mitsuya H, Parniak MA, Tedbury PR, Sarafianos SG.
Cilento ME, et al.
Viruses. 2023 Sep 25;15(10):1990. doi: 10.3390/v15101990.
Viruses. 2023.
PMID: 37896768
Free PMC article.
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Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.
McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG.
McFadden WM, et al. Among authors: cilento me.
Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012.
Cell Chem Biol. 2024.
PMID: 38518746
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Regulation of epitope exposure in the gp41 membrane-proximal external region through interactions at the apex of HIV-1 Env.
Schapiro HM, Khasnis MD, Ahn K, Karagiaridi A, Hayden S, Cilento ME, Root MJ.
Schapiro HM, et al. Among authors: cilento me.
PLoS Pathog. 2022 May 18;18(5):e1010531. doi: 10.1371/journal.ppat.1010531. eCollection 2022 May.
PLoS Pathog. 2022.
PMID: 35584191
Free PMC article.
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