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A venetoclax and azacitidine bridge-to-transplant strategy for NPM1-mutated acute myeloid leukaemia in molecular failure.
Sartor C, Brunetti L, Audisio E, Cignetti A, Zannoni L, Cristiano G, Nanni J, Ciruolo R, Zingarelli F, Ottaviani E, Patuelli A, Bandini L, Forte D, Sciabolacci S, Cardinali V, Papayannidis C, Cavo M, Martelli MP, Curti A. Sartor C, et al. Among authors: cignetti a. Br J Haematol. 2023 Aug;202(3):599-607. doi: 10.1111/bjh.18887. Epub 2023 May 24. Br J Haematol. 2023. PMID: 37226312
Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study.
Ocadlikova D, Lussana F, Fracchiolla N, Bonifacio M, Santoro L, Delia M, Chiaretti S, Pasciolla C, Cignetti A, Forghieri F, Grimaldi F, Corradi G, Zannoni L, De Propris S, Borleri GM, Tanasi I, Vadakekolathu J, Rutella S, Guarini AR, Foà R, Curti A; Campus ALL. Ocadlikova D, et al. Among authors: cignetti a. Br J Haematol. 2023 Nov;203(4):637-650. doi: 10.1111/bjh.19104. Epub 2023 Sep 12. Br J Haematol. 2023. PMID: 37700538 Free article.
SARS-CoV-2 vaccination in 361 non-transplanted patients with aplastic anemia and/or paroxysmal nocturnal hemoglobinuria.
Griffin M, Eikema DJ, Verheggen I, Kulagin A, Tjon JM, Fattizzo B, Ingram W, Zaidi U, Desnica L, Giammarco S, Drozd-Sokolowska J, Xicoy B, Patriarca A, Loschi M, Szmigielska-Kaplon A, Beier F, Cignetti A, Drexler B, Gavriilaki E, Lanza F, Orvain C, Risitano AM, De la Camara R, De Latour RP. Griffin M, et al. Among authors: cignetti a. Haematologica. 2024 Jan 1;109(1):283-286. doi: 10.3324/haematol.2023.283863. Haematologica. 2024. PMID: 37584297 Free PMC article. No abstract available.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety.
Sainas S, Giorgis M, Circosta P, Poli G, Alberti M, Passoni A, Gaidano V, Pippione AC, Vitale N, Bonanni D, Rolando B, Cignetti A, Ramondetti C, Lanno A, Ferraris DM, Canepa B, Buccinnà B, Piccinini M, Rizzi M, Saglio G, Al-Karadaghi S, Boschi D, Miggiano R, Tuccinardi T, Lolli ML. Sainas S, et al. Among authors: cignetti a. J Med Chem. 2022 Oct 13;65(19):12701-12724. doi: 10.1021/acs.jmedchem.2c00496. Epub 2022 Sep 26. J Med Chem. 2022. PMID: 36162075 Free PMC article.
Full chimaeric CAR.CIK from patients engrafted after allogeneic haematopoietic cell transplant: Feasibility, anti-leukaemic potential and alloreactivity across major human leukocyte antigen barriers.
Circosta P, Donini C, Gallo S, Giraudo L, Gammaitoni L, Rotolo R, Galvagno F, Capellero S, Basiricò M, Casucci M, Aglietta M, Ferrero I, Fagioli F, Cignetti A, Carnevale-Schianca F, Leuci V, Sangiolo D. Circosta P, et al. Among authors: cignetti a. Br J Haematol. 2023 Jan;200(1):64-69. doi: 10.1111/bjh.18469. Epub 2022 Sep 26. Br J Haematol. 2023. PMID: 36155897 Free PMC article.
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia.
Houshmand M, Vitale N, Orso F, Cignetti A, Molineris I, Gaidano V, Sainas S, Giorgis M, Boschi D, Fava C, Passoni A, Gai M, Geuna M, Sora F, Iurlo A, Abruzzese E, Breccia M, Mulas O, Caocci G, Castagnetti F, Taverna D, Oliviero S, Pane F, Lolli ML, Circosta P, Saglio G. Houshmand M, et al. Among authors: cignetti a. Cell Death Dis. 2022 Jun 30;13(6):576. doi: 10.1038/s41419-022-05028-9. Cell Death Dis. 2022. PMID: 35773274 Free PMC article.
Shedding Light on Targeting Chronic Myeloid Leukemia Stem Cells.
Houshmand M, Kazemi A, Anjam Najmedini A, Ali MS, Gaidano V, Cignetti A, Fava C, Cilloni D, Saglio G, Circosta P. Houshmand M, et al. Among authors: cignetti a. J Clin Med. 2021 Dec 11;10(24):5805. doi: 10.3390/jcm10245805. J Clin Med. 2021. PMID: 34945101 Free PMC article. Review.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety.
Sainas S, Giorgis M, Circosta P, Gaidano V, Bonanni D, Pippione AC, Bagnati R, Passoni A, Qiu Y, Cojocaru CF, Canepa B, Bona A, Rolando B, Mishina M, Ramondetti C, Buccinnà B, Piccinini M, Houshmand M, Cignetti A, Giraudo E, Al-Karadaghi S, Boschi D, Saglio G, Lolli ML. Sainas S, et al. Among authors: cignetti a. J Med Chem. 2021 May 13;64(9):5404-5428. doi: 10.1021/acs.jmedchem.0c01549. Epub 2021 Apr 12. J Med Chem. 2021. PMID: 33844533 Free PMC article.
Targeting Chronic Myeloid Leukemia Stem/Progenitor Cells Using Venetoclax-Loaded Immunoliposome.
Houshmand M, Garello F, Stefania R, Gaidano V, Cignetti A, Spinelli M, Fava C, Nikougoftar Zarif M, Galimberti S, Pungolino E, Annunziata M, Luciano L, Specchia G, Bocchia M, Binotto G, Bonifacio M, Martino B, Pregno P, Stagno F, Iurlo A, Russo S, Aime S, Circosta P, Saglio G. Houshmand M, et al. Among authors: cignetti a. Cancers (Basel). 2021 Mar 15;13(6):1311. doi: 10.3390/cancers13061311. Cancers (Basel). 2021. PMID: 33804056 Free PMC article.
73 results