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Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease.
Gaspar L, Coron RP, KongThoo Lin P, Costa DM, Perez-Cabezas B, Tavares J, Roura-Ferrer M, Ramos I, Ronin C, Major LL, Ciesielski F, Pemberton IK, MacDougall J, Ciapetti P, Smith TK, Cordeiro-da-Silva A. Gaspar L, et al. Among authors: ciesielski f. PLoS Negl Trop Dis. 2018 Jan 22;12(1):e0006180. doi: 10.1371/journal.pntd.0006180. eCollection 2018 Jan. PLoS Negl Trop Dis. 2018. PMID: 29357372 Free PMC article.
The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: Implications to protein function and drug design.
Ronin C, Costa DM, Tavares J, Faria J, Ciesielski F, Ciapetti P, Smith TK, MacDougall J, Cordeiro-da-Silva A, Pemberton IK. Ronin C, et al. Among authors: ciesielski f. PLoS One. 2018 Mar 15;13(3):e0193602. doi: 10.1371/journal.pone.0193602. eCollection 2018. PLoS One. 2018. PMID: 29543820 Free PMC article.
Toward Chemical Validation of Leishmania infantum Ribose 5-Phosphate Isomerase as a Drug Target.
Dickie EA, Ronin C, Sá M, Ciesielski F, Trouche N, Tavares J, Santarem N, Major LL, Pemberton IK, MacDougall J, Smith TK, Cordeiro-da-Silva A, Ciapetti P. Dickie EA, et al. Among authors: ciesielski f. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0189220. doi: 10.1128/AAC.01892-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875438 Free PMC article.
Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB.
Murray MH, Valfort AC, Koelblen T, Ronin C, Ciesielski F, Chatterjee A, Veerakanellore GB, Elgendy B, Walker JK, Hegazy L, Burris TP. Murray MH, et al. Among authors: ciesielski f. Nat Commun. 2022 Nov 21;13(1):7131. doi: 10.1038/s41467-022-34892-4. Nat Commun. 2022. PMID: 36414641 Free PMC article.
Discovery of phenoxyindazoles and phenylthioindazoles as RORγ inverse agonists.
Ouvry G, Bouix-Peter C, Ciesielski F, Chantalat L, Christin O, Comino C, Duvert D, Feret C, Harris CS, Lamy L, Luzy AP, Musicki B, Orfila D, Pascau J, Parnet V, Perrin A, Pierre R, Polge G, Raffin C, Rival Y, Taquet N, Thoreau E, Hennequin LF. Ouvry G, et al. Among authors: ciesielski f. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5802-5808. doi: 10.1016/j.bmcl.2016.10.023. Epub 2016 Oct 12. Bioorg Med Chem Lett. 2016. PMID: 27815118
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