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Structural determinants of limited proteolysis.
Kazanov MD, Igarashi Y, Eroshkin AM, Cieplak P, Ratnikov B, Zhang Y, Li Z, Godzik A, Osterman AL, Smith JW. Kazanov MD, et al. Among authors: cieplak p. J Proteome Res. 2011 Aug 5;10(8):3642-51. doi: 10.1021/pr200271w. Epub 2011 Jul 8. J Proteome Res. 2011. PMID: 21682278 Free PMC article.
Substrate cleavage analysis of furin and related proprotein convertases. A comparative study.
Remacle AG, Shiryaev SA, Oh ES, Cieplak P, Srinivasan A, Wei G, Liddington RC, Ratnikov BI, Parent A, Desjardins R, Day R, Smith JW, Lebl M, Strongin AY. Remacle AG, et al. Among authors: cieplak p. J Biol Chem. 2008 Jul 25;283(30):20897-906. doi: 10.1074/jbc.M803762200. Epub 2008 May 27. J Biol Chem. 2008. PMID: 18505722 Free PMC article.
Synthesis of novel beta-lactone inhibitors of fatty acid synthase.
Richardson RD, Ma G, Oyola Y, Zancanella M, Knowles LM, Cieplak P, Romo D, Smith JW. Richardson RD, et al. Among authors: cieplak p. J Med Chem. 2008 Sep 11;51(17):5285-96. doi: 10.1021/jm800321h. Epub 2008 Aug 19. J Med Chem. 2008. PMID: 18710210 Free PMC article.
PMAP: databases for analyzing proteolytic events and pathways.
Igarashi Y, Heureux E, Doctor KS, Talwar P, Gramatikova S, Gramatikoff K, Zhang Y, Blinov M, Ibragimova SS, Boyd S, Ratnikov B, Cieplak P, Godzik A, Smith JW, Osterman AL, Eroshkin AM. Igarashi Y, et al. Among authors: cieplak p. Nucleic Acids Res. 2009 Jan;37(Database issue):D611-8. doi: 10.1093/nar/gkn683. Epub 2008 Oct 8. Nucleic Acids Res. 2009. PMID: 18842634 Free PMC article.
Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.
Shiryaev SA, Remacle AG, Savinov AY, Chernov AV, Cieplak P, Radichev IA, Williams R, Shiryaeva TN, Gawlik K, Postnova TI, Ratnikov BI, Eroshkin AM, Motamedchaboki K, Smith JW, Strongin AY. Shiryaev SA, et al. Among authors: cieplak p. J Biol Chem. 2009 Oct 30;284(44):30615-26. doi: 10.1074/jbc.M109.041244. Epub 2009 Sep 2. J Biol Chem. 2009. PMID: 19726693 Free PMC article.
Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.
Golubkov VS, Cieplak P, Chekanov AV, Ratnikov BI, Aleshin AE, Golubkova NV, Postnova TI, Radichev IA, Rozanov DV, Zhu W, Motamedchaboki K, Strongin AY. Golubkov VS, et al. Among authors: cieplak p. J Biol Chem. 2010 Sep 3;285(36):27726-36. doi: 10.1074/jbc.M110.135442. Epub 2010 Jul 6. J Biol Chem. 2010. PMID: 20605791 Free PMC article.
97 results