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Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma.
Iida Y, Ciechanover A, Marzese DM, Hata K, Bustos M, Ono S, Wang J, Salomon MP, Tran K, Lam S, Hsu S, Nelson N, Kravtsova-Ivantsiv Y, Mills GB, Davies MA, Hoon DSB. Iida Y, et al. Among authors: ciechanover a. Clin Cancer Res. 2017 Aug 15;23(16):4831-4842. doi: 10.1158/1078-0432.CCR-17-0146. Epub 2017 Apr 7. Clin Cancer Res. 2017. PMID: 28389511 Free PMC article.
Excess of the NF-ĸB p50 subunit generated by the ubiquitin ligase KPC1 suppresses tumors via PD-L1- and chemokines-mediated mechanisms.
Kravtsova-Ivantsiv Y, Goldhirsh G, Ivantsiv A, Ben Itzhak O, Kwon YT, Pikarsky E, Ciechanover A. Kravtsova-Ivantsiv Y, et al. Among authors: ciechanover a. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29823-29831. doi: 10.1073/pnas.2019604117. Epub 2020 Nov 9. Proc Natl Acad Sci U S A. 2020. PMID: 33168738 Free PMC article.
300 results