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Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma.
Cichocki F, Bjordahl R, Goodridge JP, Mahmood S, Gaidarova S, Abujarour R, Davis ZB, Merino A, Tuininga K, Wang H, Kumar A, Groff B, Witty A, Bonello G, Huffman J, Dailey T, Lee TT, Malmberg KJ, Walcheck B, Höpken U, Rehm A, Valamehr B, Miller JS. Cichocki F, et al. Nat Commun. 2022 Nov 29;13(1):7341. doi: 10.1038/s41467-022-35127-2. Nat Commun. 2022. PMID: 36446823 Free PMC article.
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9.
Gleason MK, Lenvik TR, McCullar V, Felices M, O'Brien MS, Cooley SA, Verneris MR, Cichocki F, Holman CJ, Panoskaltsis-Mortari A, Niki T, Hirashima M, Blazar BR, Miller JS. Gleason MK, et al. Among authors: cichocki f. Blood. 2012 Mar 29;119(13):3064-72. doi: 10.1182/blood-2011-06-360321. Epub 2012 Feb 8. Blood. 2012. PMID: 22323453 Free PMC article.
60 results