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Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibition.
Ehrmann FR, Stojko J, Metz A, Debaene F, Barandun LJ, Heine A, Diederich F, Cianférani S, Reuter K, Klebe G. Ehrmann FR, et al. Among authors: cianferani s. PLoS One. 2017 Apr 18;12(4):e0175723. doi: 10.1371/journal.pone.0175723. eCollection 2017. PLoS One. 2017. PMID: 28419165 Free PMC article.
Hyphenation of size exclusion chromatography to native ion mobility mass spectrometry for the analytical characterization of therapeutic antibodies and related products.
Ehkirch A, Hernandez-Alba O, Colas O, Beck A, Guillarme D, Cianférani S. Ehkirch A, et al. Among authors: cianferani s. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Jun 1;1086:176-183. doi: 10.1016/j.jchromb.2018.04.010. Epub 2018 Apr 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29684909
181 results