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Unraveling the genetics of arsenic toxicity with cellular morphology QTL.
O'Connor C, Keele GR, Martin W, Stodola T, Gatti D, Hoffman BR, Korstanje R, Churchill GA, Reinholdt LG. O'Connor C, et al. Among authors: churchill ga. PLoS Genet. 2024 Apr 25;20(4):e1011248. doi: 10.1371/journal.pgen.1011248. eCollection 2024 Apr. PLoS Genet. 2024. PMID: 38662777 Free PMC article.
Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.
Dumont BL, Gatti DM, Ballinger MA, Lin D, Phifer-Rixey M, Sheehan MJ, Suzuki TA, Wooldridge LK, Frempong HO, Lawal RA, Churchill GA, Lutz C, Rosenthal N, White JK, Nachman MW. Dumont BL, et al. Among authors: churchill ga. PLoS Genet. 2024 Apr 10;20(4):e1011228. doi: 10.1371/journal.pgen.1011228. eCollection 2024 Apr. PLoS Genet. 2024. PMID: 38598567 Free PMC article.
Genetic regulation of carnitine metabolism controls lipid damage repair and aging RBC hemolysis in vivo and in vitro.
Nemkov T, Key A, Stephenson D, Earley EJ, Keele GR, Hay AM, Amireault P, Casimir M, Dussiot M, Dzieciatkowska M, Reisz JA, Deng X, Stone M, Kleinman SH, Spitalnik SL, Hansen KC, Norris PJ, Churchill GA, Busch MP, Roubinian NH, Page GP, Zimring JC, Arduini A, D'Alessandro A. Nemkov T, et al. Among authors: churchill ga. Blood. 2024 Mar 21:blood.2024023983. doi: 10.1182/blood.2024023983. Online ahead of print. Blood. 2024. PMID: 38513237
GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis.
Ball RL, Bogue MA, Liang H, Srivastava A, Ashbrook DG, Lamoureux A, Gerring MW, Hatoum AS, Kim MJ, He H, Emerson J, Berger AK, Walton DO, Sheppard K, El Kassaby B, Castellanos F, Kunde-Ramamoorthy G, Lu L, Bluis J, Desai S, Sundberg BA, Peltz G, Fang Z, Churchill GA, Williams RW, Agrawal A, Bult CJ, Philip VM, Chesler EJ. Ball RL, et al. Among authors: churchill ga. Genome Res. 2024 Feb 7;34(1):145-159. doi: 10.1101/gr.278157.123. Genome Res. 2024. PMID: 38290977 Free PMC article.
Biological and Genetic Determinants of Glycolysis: Phosphofructokinase Isoforms Boost Energy Status of Stored Red Blood Cells and Transfusion Outcomes.
Nemkov T, Stephenson D, Earley EJ, Keele GR, Hay A, Key A, Haiman Z, Erickson C, Dzieciatkowska M, Reisz JA, Moore A, Stone M, Deng X, Kleinman S, Spitalnik SL, Hod EA, Hudson KE, Hansen KC, Palsson BO, Churchill GA, Roubinian N, Norris PJ, Busch MP, Zimring JC, Page GP, D'Alessandro A. Nemkov T, et al. Among authors: churchill ga. bioRxiv [Preprint]. 2024 Apr 17:2023.09.11.557250. doi: 10.1101/2023.09.11.557250. bioRxiv. 2024. PMID: 38260479 Free PMC article. Preprint.
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice.
Gatti DM, Tyler AL, Mahoney JM, Churchill GA, Yener B, Koyuncu D, Gurcan MN, Niazi M, Tavolara T, Gower AC, Dayao D, McGlone E, Ginese ML, Specht A, Alsharaydeh A, Tessier PA, Kurtz SL, Elkins K, Kramnik I, Beamer G. Gatti DM, et al. Among authors: churchill ga. bioRxiv [Preprint]. 2023 Dec 22:2023.12.21.572738. doi: 10.1101/2023.12.21.572738. bioRxiv. 2023. PMID: 38187647 Free PMC article. Preprint.
Examination of betahistine bioavailability in combination with the monoamine oxidase B inhibitor, selegiline, in humans-a non-randomized, single-sequence, two-period titration, open label single-center phase 1 study (PK-BeST).
Strupp M, Churchill GC, Naumann I, Mansmann U, Al Tawil A, Golentsova A, Goldschagg N. Strupp M, et al. Among authors: churchill gc. Front Neurol. 2023 Oct 18;14:1271640. doi: 10.3389/fneur.2023.1271640. eCollection 2023. Front Neurol. 2023. PMID: 37920833 Free PMC article.
439 results