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Next-Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development.
Roth SE, Avigan MI, Bourdet D, Brott D, Church R, Dash A, Keller D, Sherratt P, Watkins PB, Westcott-Baker L, Lentini S, Merz M, Ramaiah L, Ramaiah SK, Stanley AM, Marcinak J. Roth SE, et al. Among authors: church r. Clin Pharmacol Ther. 2020 Feb;107(2):333-346. doi: 10.1002/cpt.1571. Epub 2019 Sep 14. Clin Pharmacol Ther. 2020. PMID: 31314926 Free PMC article. Review.
Candidate biomarkers for the diagnosis and prognosis of drug-induced liver injury: An international collaborative effort.
Church RJ, Kullak-Ublick GA, Aubrecht J, Bonkovsky HL, Chalasani N, Fontana RJ, Goepfert JC, Hackman F, King NMP, Kirby S, Kirby P, Marcinak J, Ormarsdottir S, Schomaker SJ, Schuppe-Koistinen I, Wolenski F, Arber N, Merz M, Sauer JM, Andrade RJ, van Bömmel F, Poynard T, Watkins PB. Church RJ, et al. Hepatology. 2019 Feb;69(2):760-773. doi: 10.1002/hep.29802. Epub 2018 Jun 27. Hepatology. 2019. PMID: 29357190 Free PMC article.
Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors.
Woodhead JL, Brock WJ, Roth SE, Shoaf SE, Brouwer KL, Church R, Grammatopoulos TN, Stiles L, Siler SQ, Howell BA, Mosedale M, Watkins PB, Shoda LK. Woodhead JL, et al. Among authors: church r. Toxicol Sci. 2017 Jan;155(1):61-74. doi: 10.1093/toxsci/kfw193. Epub 2016 Sep 21. Toxicol Sci. 2017. PMID: 27655350 Free PMC article.
Reply.
Church RJ, Watkins PB. Church RJ, et al. Hepatology. 2018 Jun;67(6):2481-2482. doi: 10.1002/hep.29863. Epub 2018 May 1. Hepatology. 2018. PMID: 29506324 No abstract available.
383 results