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Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.
Jiang Z, Li H, Schroer SA, Voisin V, Ju Y, Pacal M, Erdmann N, Shi W, Chung PED, Deng T, Chen NJ, Ciavarra G, Datti A, Mak TW, Harrington L, Dick FA, Bader GD, Bremner R, Woo M, Zacksenhaus E. Jiang Z, et al. Among authors: chung ped. EMBO J. 2022 Feb 15;41(4):e106825. doi: 10.15252/embj.2020106825. Epub 2022 Jan 13. EMBO J. 2022. PMID: 35023164 Free PMC article.
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.
Jiang Z, Jones R, Liu JC, Deng T, Robinson T, Chung PE, Wang S, Herschkowitz JI, Egan SE, Perou CM, Zacksenhaus E. Jiang Z, et al. Cell Cycle. 2011 May 15;10(10):1563-70. doi: 10.4161/cc.10.10.15703. Epub 2011 May 15. Cell Cycle. 2011. PMID: 21502814 Review.
Targeting HER2(+) breast cancer: the TBK1/IKKε axis.
Jiang Z, Liu JC, Chung PE, Egan SE, Zacksenhaus E. Jiang Z, et al. Oncoscience. 2014 Mar 6;1(2):180-2. doi: 10.18632/oncoscience.18. eCollection 2014. Oncoscience. 2014. PMID: 25594009 Free PMC article.
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
Jones RA, Robinson TJ, Liu JC, Shrestha M, Voisin V, Ju Y, Chung PE, Pellecchia G, Fell VL, Bae S, Muthuswamy L, Datti A, Egan SE, Jiang Z, Leone G, Bader GD, Schimmer A, Zacksenhaus E. Jones RA, et al. J Clin Invest. 2016 Oct 3;126(10):3739-3757. doi: 10.1172/JCI81568. Epub 2016 Aug 29. J Clin Invest. 2016. PMID: 27571409 Free PMC article.
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Chung PED, Gendoo DMA, Ghanbari-Azarnier R, Liu JC, Jiang Z, Tsui J, Wang DY, Xiao X, Li B, Dubuc A, Shih D, Remke M, Ho B, Garzia L, Ben-David Y, Kang SG, Croul S, Haibe-Kains B, Huang A, Taylor MD, Zacksenhaus E. Chung PED, et al. Nat Commun. 2020 Apr 14;11(1):1825. doi: 10.1038/s41467-020-15585-2. Nat Commun. 2020. PMID: 32286280 Free PMC article.
Methylation data of mouse Rb-deficient pineoblastoma.
Chung PED, Zacksenhaus E. Chung PED, et al. Data Brief. 2020 Aug 25;32:106229. doi: 10.1016/j.dib.2020.106229. eCollection 2020 Oct. Data Brief. 2020. PMID: 32923545 Free PMC article.
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer.
Jiang Z, Ju Y, Ali A, Chung PED, Skowron P, Wang DY, Shrestha M, Li H, Liu JC, Vorobieva I, Ghanbari-Azarnier R, Mwewa E, Koritzinsky M, Ben-David Y, Woodgett JR, Perou CM, Dupuy A, Bader GD, Egan SE, Taylor MD, Zacksenhaus E. Jiang Z, et al. Among authors: chung ped. Nat Commun. 2023 Jul 18;14(1):4313. doi: 10.1038/s41467-023-39935-y. Nat Commun. 2023. PMID: 37463901 Free PMC article.
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