Chung MC - Search Results

1

Synthesis, characterization and pharmacological evaluation of 1-(2-chloro-6-fluorophenyl)-5-methylindolin-2-one: a new anti-inflammatory compound with reduced gastric ulceration properties.

dos Santos JL, Chelucci R, Chiquetto R, Chung MC, Campos ML, Peccinini RG. dos Santos JL, et al. Among authors: chung mc. Molecules. 2010 Nov 8;15(11):8039-47. doi: 10.3390/molecules15118039. Molecules. 2010. PMID: 21060305 Free PMC article.

2

Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties.

Chung MC, dos Santos JL, Oliveira EV, Blau L, Menegon RF, Peccinini RG. Chung MC, et al. Molecules. 2009 Aug 26;14(9):3187-97. doi: 10.3390/molecules14093187. Molecules. 2009. PMID: 19783917 Free PMC article.

3

Antiplatelet and antithrombotic activities of non-steroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

Chelucci RC, Dutra LA, Lopes Pires ME, de Melo TR, Bosquesi PL, Chung MC, Dos Santos JL. Chelucci RC, et al. Among authors: chung mc. Molecules. 2014 Feb 17;19(2):2089-99. doi: 10.3390/molecules19022089. Molecules. 2014. PMID: 24549233 Free PMC article.

4

Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.

de Melo TR, Chelucci RC, Pires ME, Dutra LA, Barbieri KP, Bosquesi PL, Trossini GH, Chung MC, dos Santos JL. de Melo TR, et al. Among authors: chung mc. Int J Mol Sci. 2014 Apr 4;15(4):5821-37. doi: 10.3390/ijms15045821. Int J Mol Sci. 2014. PMID: 24714090 Free PMC article.

5

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.

dos Santos JL, Lanaro C, Lima LM, Gambero S, Franco-Penteado CF, Alexandre-Moreira MS, Wade M, Yerigenahally S, Kutlar A, Meiler SE, Costa FF, Chung M. dos Santos JL, et al. J Med Chem. 2011 Aug 25;54(16):5811-9. doi: 10.1021/jm200531f. Epub 2011 Jul 25. J Med Chem. 2011. PMID: 21766854

6

Assessment of the in vivo genotoxicity of new lead compounds to treat sickle cell disease.

Dos Santos JL, Longhin Bosquesi P, Varanda EA, Moreira Lima L, Chung MC. Dos Santos JL, et al. Among authors: chung mc. Molecules. 2011 Apr 6;16(4):2982-9. doi: 10.3390/molecules16042982. Molecules. 2011. PMID: 21471937 Free PMC article.

7

Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms. part II: furoxan derivatives.

Dos Santos JL, Lanaro C, Chelucci RC, Gambero S, Bosquesi PL, Reis JS, Lima LM, Cerecetto H, González M, Costa FF, Chung MC. Dos Santos JL, et al. Among authors: chung mc. J Med Chem. 2012 Sep 13;55(17):7583-92. doi: 10.1021/jm300602n. Epub 2012 Aug 21. J Med Chem. 2012. PMID: 22889416

8

Pharmacokinetics of hydroxymethylnitrofurazone, a promising new prodrug for Chagas' disease treatment.

Serafim EO, Silva AT, Moreno Ade H, Vizioli Ede O, Ferreira EI, Peccinini RG, Ribeiro ML, Chung MC. Serafim EO, et al. Among authors: chung mc. Antimicrob Agents Chemother. 2013 Dec;57(12):6106-9. doi: 10.1128/AAC.02522-12. Epub 2013 Sep 30. Antimicrob Agents Chemother. 2013. PMID: 24080661 Free PMC article.

9

Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions.

Yamasaki PR, do Nascimento DC, Chelucci RC, de Faria Fernandes Belone A, Rosa PS, Diório SM, de Melo TR, Barbieri KP, Placeres MC, Carlos IZ, Chung MC, dos Santos JL. Yamasaki PR, et al. Among authors: chung mc. Bioorg Med Chem Lett. 2014 Jul 15;24(14):3084-7. doi: 10.1016/j.bmcl.2014.05.017. Epub 2014 May 16. Bioorg Med Chem Lett. 2014. PMID: 24907144

10

The Prodrug Approach: A Successful Tool for Improving Drug Solubility.

Jornada DH, dos Santos Fernandes GF, Chiba DE, de Melo TR, dos Santos JL, Chung MC. Jornada DH, et al. Among authors: chung mc. Molecules. 2015 Dec 29;21(1):42. doi: 10.3390/molecules21010042. Molecules. 2015. PMID: 26729077 Free PMC article. Review.

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