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Page 1
Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.
Kalafati L, Kourtzelis I, Schulte-Schrepping J, Li X, Hatzioannou A, Grinenko T, Hagag E, Sinha A, Has C, Dietz S, de Jesus Domingues AM, Nati M, Sormendi S, Neuwirth A, Chatzigeorgiou A, Ziogas A, Lesche M, Dahl A, Henry I, Subramanian P, Wielockx B, Murray P, Mirtschink P, Chung KJ, Schultze JL, Netea MG, Hajishengallis G, Verginis P, Mitroulis I, Chavakis T. Kalafati L, et al. Among authors: chung kj. Cell. 2020 Oct 29;183(3):771-785.e12. doi: 10.1016/j.cell.2020.09.058. Cell. 2020. PMID: 33125892 Free PMC article.
The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance.
Phieler J, Chung KJ, Chatzigeorgiou A, Klotzsche-von Ameln A, Garcia-Martin R, Sprott D, Moisidou M, Tzanavari T, Ludwig B, Baraban E, Ehrhart-Bornstein M, Bornstein SR, Mziaut H, Solimena M, Karalis KP, Economopoulou M, Lambris JD, Chavakis T. Phieler J, et al. Among authors: chung kj. J Immunol. 2013 Oct 15;191(8):4367-74. doi: 10.4049/jimmunol.1300038. Epub 2013 Sep 16. J Immunol. 2013. PMID: 24043887 Free PMC article.
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Among authors: chung kj. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation.
Chatzigeorgiou A, Chung KJ, Garcia-Martin R, Alexaki VI, Klotzsche-von Ameln A, Phieler J, Sprott D, Kanczkowski W, Tzanavari T, Bdeir M, Bergmann S, Cartellieri M, Bachmann M, Nikolakopoulou P, Androutsellis-Theotokis A, Siegert G, Bornstein SR, Muders MH, Boon L, Karalis KP, Lutgens E, Chavakis T. Chatzigeorgiou A, et al. Among authors: chung kj. Hepatology. 2014 Oct;60(4):1196-210. doi: 10.1002/hep.27233. Epub 2014 Aug 21. Hepatology. 2014. PMID: 24845056
Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.
Choi EY, Lim JH, Neuwirth A, Economopoulou M, Chatzigeorgiou A, Chung KJ, Bittner S, Lee SH, Langer H, Samus M, Kim H, Cho GS, Ziemssen T, Bdeir K, Chavakis E, Koh JY, Boon L, Hosur K, Bornstein SR, Meuth SG, Hajishengallis G, Chavakis T. Choi EY, et al. Among authors: chung kj. Mol Psychiatry. 2015 Jul;20(7):880-888. doi: 10.1038/mp.2014.146. Epub 2014 Nov 11. Mol Psychiatry. 2015. PMID: 25385367 Free PMC article.
Adipocyte-Specific Hypoxia-Inducible Factor 2α Deficiency Exacerbates Obesity-Induced Brown Adipose Tissue Dysfunction and Metabolic Dysregulation.
García-Martín R, Alexaki VI, Qin N, Rubín de Celis MF, Economopoulou M, Ziogas A, Gercken B, Kotlabova K, Phieler J, Ehrhart-Bornstein M, Bornstein SR, Eisenhofer G, Breier G, Blüher M, Hampe J, El-Armouche A, Chatzigeorgiou A, Chung KJ, Chavakis T. García-Martín R, et al. Among authors: chung kj. Mol Cell Biol. 2015 Nov 16;36(3):376-93. doi: 10.1128/MCB.00430-15. Print 2016 Feb 1. Mol Cell Biol. 2015. PMID: 26572826 Free PMC article.
No Role for Mast Cells in Obesity-Related Metabolic Dysregulation.
Chmelař J, Chatzigeorgiou A, Chung KJ, Prucnal M, Voehringer D, Roers A, Chavakis T. Chmelař J, et al. Among authors: chung kj. Front Immunol. 2016 Nov 24;7:524. doi: 10.3389/fimmu.2016.00524. eCollection 2016. Front Immunol. 2016. PMID: 27933062 Free PMC article.
A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.
Chung KJ, Chatzigeorgiou A, Economopoulou M, Garcia-Martin R, Alexaki VI, Mitroulis I, Nati M, Gebler J, Ziemssen T, Goelz SE, Phieler J, Lim JH, Karalis KP, Papayannopoulou T, Blüher M, Hajishengallis G, Chavakis T. Chung KJ, et al. Nat Immunol. 2017 Jun;18(6):654-664. doi: 10.1038/ni.3728. Epub 2017 Apr 17. Nat Immunol. 2017. PMID: 28414311 Free PMC article.
270 results