Chudasama V - Search Results

1

The use of bromopyridazinedione derivatives in chemical biology.

Bahou C, Chudasama V. Bahou C, et al. Among authors: chudasama v. Org Biomol Chem. 2022 Aug 3;20(30):5879-5890. doi: 10.1039/d2ob00310d. Org Biomol Chem. 2022. PMID: 35373804 Review.

2

Bromopyridazinedione-mediated protein and peptide bioconjugation.

Chudasama V, Smith ME, Schumacher FF, Papaioannou D, Waksman G, Baker JR, Caddick S. Chudasama V, et al. Chem Commun (Camb). 2011 Aug 21;47(31):8781-3. doi: 10.1039/c1cc12807h. Epub 2011 Jul 7. Chem Commun (Camb). 2011. PMID: 21738916 Free PMC article.

3

Reversible protein affinity-labelling using bromomaleimide-based reagents.

Nathani RI, Chudasama V, Ryan CP, Moody PR, Morgan RE, Fitzmaurice RJ, Smith ME, Baker JR, Caddick S. Nathani RI, et al. Among authors: chudasama v. Org Biomol Chem. 2013 Apr 21;11(15):2408-11. doi: 10.1039/c3ob40239h. Epub 2013 Mar 5. Org Biomol Chem. 2013. PMID: 23462873 Free PMC article.

4

Next generation maleimides enable the controlled assembly of antibody-drug conjugates via native disulfide bond bridging.

Schumacher FF, Nunes JP, Maruani A, Chudasama V, Smith ME, Chester KA, Baker JR, Caddick S. Schumacher FF, et al. Among authors: chudasama v. Org Biomol Chem. 2014 Oct 7;12(37):7261-9. doi: 10.1039/c4ob01550a. Org Biomol Chem. 2014. PMID: 25103319 Free PMC article.

5

A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation.

Morgan RE, Chudasama V, Moody P, Smith ME, Caddick S. Morgan RE, et al. Among authors: chudasama v. Org Biomol Chem. 2015 Apr 14;13(14):4165-8. doi: 10.1039/c5ob00130g. Epub 2015 Mar 4. Org Biomol Chem. 2015. PMID: 25736233 Free PMC article.

6

A platform for efficient, thiol-stable conjugation to albumin's native single accessible cysteine.

Smith ME, Caspersen MB, Robinson E, Morais M, Maruani A, Nunes JP, Nicholls K, Saxton MJ, Caddick S, Baker JR, Chudasama V. Smith ME, et al. Among authors: chudasama v. Org Biomol Chem. 2015 Aug 7;13(29):7946-9. doi: 10.1039/c5ob01205h. Epub 2015 Jun 25. Org Biomol Chem. 2015. PMID: 26108475 Free PMC article.

7

Photochemically re-bridging disulfide bonds and the discovery of a thiomaleimide mediated photodecarboxylation of C-terminal cysteines.

Richards DA, Fletcher SA, Nobles M, Kossen H, Tedaldi L, Chudasama V, Tinker A, Baker JR. Richards DA, et al. Among authors: chudasama v. Org Biomol Chem. 2016 Jan 14;14(2):455-459. doi: 10.1039/c5ob02120k. Org Biomol Chem. 2016. PMID: 26603469

8

Identification of an active metabolite of PAR-1 antagonist RWJ-58259 and synthesis of analogues to enhance its metabolic stability.

Robinson E, Knight E, Smoktunowicz N, Chambers RC, Inglis GG, Chudasama V, Caddick S. Robinson E, et al. Among authors: chudasama v. Org Biomol Chem. 2016 Mar 28;14(12):3198-201. doi: 10.1039/c6ob00332j. Org Biomol Chem. 2016. PMID: 26927018

9

Synthesis of novel and potent vorapaxar analogues.

Knight E, Robinson E, Smoktunowicz N, Chambers RC, Aliev AE, Inglis GG, Chudasama V, Caddick S. Knight E, et al. Among authors: chudasama v. Org Biomol Chem. 2016 Mar 28;14(12):3264-74. doi: 10.1039/c5ob02541a. Org Biomol Chem. 2016. PMID: 26932831 Free article.

10

Dual modification of biomolecules.

Maruani A, Richards DA, Chudasama V. Maruani A, et al. Among authors: chudasama v. Org Biomol Chem. 2016 Jul 14;14(26):6165-78. doi: 10.1039/c6ob01010e. Epub 2016 Jun 9. Org Biomol Chem. 2016. PMID: 27278999 Review.

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