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Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass.
Maupin KA, Himes ER, Plett AP, Chua HL, Singh P, Ghosh J, Mohamad SF, Abeysekera I, Fisher A, Sampson C, Hong JM, Childress P, Alvarez M, Srour EF, Bruzzaniti A, Pelus LM, Orschell CM, Kacena MA. Maupin KA, et al. Among authors: chua hl. Bone. 2019 Oct;127:452-459. doi: 10.1016/j.bone.2019.07.010. Epub 2019 Jul 9. Bone. 2019. PMID: 31299382 Free PMC article.
Pyk2 regulates megakaryocyte-induced increases in osteoblast number and bone formation.
Cheng YH, Hooker RA, Nguyen K, Gerard-O'Riley R, Waning DL, Chitteti BR, Meijome TE, Chua HL, Plett AP, Orschell CM, Srour EF, Mayo LD, Pavalko FM, Bruzzaniti A, Kacena MA. Cheng YH, et al. Among authors: chua hl. J Bone Miner Res. 2013 Jun;28(6):1434-45. doi: 10.1002/jbmr.1876. J Bone Miner Res. 2013. PMID: 23362087 Free PMC article.
The H-ARS Dose Response Relationship (DRR): Validation and Variables.
Plett PA, Sampson CH, Chua HL, Jackson W, Vemula S, Sellamuthu R, Fisher A, Feng H, Wu T, MacVittie TJ, Orschell CM. Plett PA, et al. Among authors: chua hl. Health Phys. 2015 Nov;109(5):391-8. doi: 10.1097/HP.0000000000000354. Health Phys. 2015. PMID: 26425900 Free PMC article.
Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to <10 Gy Total Body Irradiation.
Unthank JL, Miller SJ, Quickery AK, Ferguson EL, Wang M, Sampson CH, Chua HL, DiStasi MR, Feng H, Fisher A, Katz BP, Plett PA, Sandusky GE, Sellamuthu R, Vemula S, Cohen EP, MacVittie TJ, Orschell CM. Unthank JL, et al. Among authors: chua hl. Health Phys. 2015 Nov;109(5):511-21. doi: 10.1097/HP.0000000000000357. Health Phys. 2015. PMID: 26425910 Free PMC article.
Characterization and Etiology of Swollen Muzzles in Irradiated Mice.
Garrett J, Sampson CH, Plett PA, Crisler R, Parker J, Venezia R, Chua HL, Hickman DL, Booth C, MacVittie T, Orschell CM, Dynlacht JR. Garrett J, et al. Among authors: chua hl. Radiat Res. 2019 Jan;191(1):31-42. doi: 10.1667/RR14724.1. Epub 2018 Oct 19. Radiat Res. 2019. PMID: 30339056
40 results