Chu X - Search Results

1

Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug-Drug Interaction Evaluation: Perspectives From the International Transporter Consortium.

Chu X, Liao M, Shen H, Yoshida K, Zur AA, Arya V, Galetin A, Giacomini KM, Hanna I, Kusuhara H, Lai Y, Rodrigues D, Sugiyama Y, Zamek-Gliszczynski MJ, Zhang L; International Transporter Consortium. Chu X, et al. Clin Pharmacol Ther. 2018 Nov;104(5):836-864. doi: 10.1002/cpt.1216. Clin Pharmacol Ther. 2018. PMID: 30347454 Review.

2

Multispecific organic anion transporter is responsible for the biliary excretion of the camptothecin derivative irinotecan and its metabolites in rats.

Chu XY, Kato Y, Niinuma K, Sudo KI, Hakusui H, Sugiyama Y. Chu XY, et al. J Pharmacol Exp Ther. 1997 Apr;281(1):304-14. J Pharmacol Exp Ther. 1997. PMID: 9103511

3

Multiplicity of biliary excretion mechanisms for irinotecan, CPT-11, and its metabolites in rats.

Chu XY, Kato Y, Sugiyama Y. Chu XY, et al. Cancer Res. 1997 May 15;57(10):1934-8. Cancer Res. 1997. PMID: 9157988

4

Multiplicity of biliary excretion mechanisms for the camptothecin derivative irinotecan (CPT-11), its metabolite SN-38, and its glucuronide: role of canalicular multispecific organic anion transporter and P-glycoprotein.

Sugiyama Y, Kato Y, Chu X. Sugiyama Y, et al. Among authors: chu x. Cancer Chemother Pharmacol. 1998;42 Suppl:S44-9. doi: 10.1007/s002800051078. Cancer Chemother Pharmacol. 1998. PMID: 9750028 Review.

5

Active efflux of CPT-11 and its metabolites in human KB-derived cell lines.

Chu XY, Suzuki H, Ueda K, Kato Y, Akiyama S, Sugiyama Y. Chu XY, et al. J Pharmacol Exp Ther. 1999 Feb;288(2):735-41. J Pharmacol Exp Ther. 1999. PMID: 9918583

6

Possible involvement of P-glycoprotein in biliary excretion of CPT-11 in rats.

Chu XY, Kato Y, Sugiyama Y. Chu XY, et al. Drug Metab Dispos. 1999 Apr;27(4):440-1. Drug Metab Dispos. 1999. PMID: 10101137

7

Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2).

Hirohashi T, Suzuki H, Chu XY, Tamai I, Tsuji A, Sugiyama Y. Hirohashi T, et al. Among authors: chu xy. J Pharmacol Exp Ther. 2000 Jan;292(1):265-70. J Pharmacol Exp Ther. 2000. PMID: 10604957

8

Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3.

Chu XY, Huskey SE, Braun MP, Sarkadi B, Evans DC, Evers R. Chu XY, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):156-64. doi: 10.1124/jpet.103.062091. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722317

9

Membrane transporters in drug development.

International Transporter Consortium; Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. International Transporter Consortium, et al. Among authors: chu x. Nat Rev Drug Discov. 2010 Mar;9(3):215-36. doi: 10.1038/nrd3028. Nat Rev Drug Discov. 2010. PMID: 20190787 Free PMC article. Review.

10

Rifampin's acute inhibitory and chronic inductive drug interactions: experimental and model-based approaches to drug-drug interaction trial design.

Reitman ML, Chu X, Cai X, Yabut J, Venkatasubramanian R, Zajic S, Stone JA, Ding Y, Witter R, Gibson C, Roupe K, Evers R, Wagner JA, Stoch A. Reitman ML, et al. Among authors: chu x. Clin Pharmacol Ther. 2011 Feb;89(2):234-42. doi: 10.1038/clpt.2010.271. Epub 2010 Dec 29. Clin Pharmacol Ther. 2011. PMID: 21191377

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