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Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein.
Ferguson AD, McKeever BM, Xu S, Wisniewski D, Miller DK, Yamin TT, Spencer RH, Chu L, Ujjainwalla F, Cunningham BR, Evans JF, Becker JW. Ferguson AD, et al. Among authors: chu l. Science. 2007 Jul 27;317(5837):510-2. doi: 10.1126/science.1144346. Epub 2007 Jun 28. Science. 2007. PMID: 17600184
Expression, purification and crystallization of human 5-lipoxygenase-activating protein with leukotriene-biosynthesis inhibitors.
Xu S, McKeever BM, Wisniewski D, Miller DK, Spencer RH, Chu L, Ujjainwalla F, Yamin TT, Evans JF, Becker JW, Ferguson AD. Xu S, et al. Among authors: chu l. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1054-7. doi: 10.1107/S1744309107055571. Epub 2007 Nov 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 18084092 Free PMC article.
Evaluation of endo- and exo-aryl-substitutions and central scaffold modifications on diphenyl substituted alkanes as 5-lipoxygenase activating protein inhibitors.
Chu L, Armstrong HM, Chang LL, Cheng AF, Colwell L, Cui J, Evans J, Galka A, Goulet MT, Hayes N, Lo J, Menke J, Ok HO, Ondeyka DL, Patel M, Quaker GM, Sings H, Witkin SL, Zhao A, Ujjainwalla F. Chu L, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4133-8. doi: 10.1016/j.bmcl.2012.04.064. Epub 2012 Apr 20. Bioorg Med Chem Lett. 2012. PMID: 22578458
Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques.
Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ. Wickham LA, et al. Among authors: chu l. Thromb Res. 2016 Sep;145:133-9. doi: 10.1016/j.thromres.2016.06.007. Epub 2016 Jun 11. Thromb Res. 2016. PMID: 27318768
Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.
Wang X, Kurowski S, Wu W, Castriota GA, Zhou X, Chu L, Ellsworth KP, Chu D, Edmondson S, Ali A, Andre P, Seiffert D, Erion M, Gutstein DE, Chen Z. Wang X, et al. Among authors: chu d, chu l. J Pharmacol Exp Ther. 2017 Mar;360(3):476-483. doi: 10.1124/jpet.116.238600. Epub 2016 Dec 29. J Pharmacol Exp Ther. 2017. PMID: 28035007
Early detection of pancreatic cancer in the era of precision medicine.
Ahmed TM, Kawamoto S, Lopez-Ramirez F, Yasrab M, Hruban RH, Fishman EK, Chu LC. Ahmed TM, et al. Among authors: chu lc. Abdom Radiol (NY). 2024 May 18. doi: 10.1007/s00261-024-04358-w. Online ahead of print. Abdom Radiol (NY). 2024. PMID: 38761272 Review.
3,113 results