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First-in-Class Small Molecule to Inhibit CYP11A1 and Steroid Hormone Biosynthesis.
Karimaa M, Riikonen R, Kettunen H, Taavitsainen P, Ramela M, Chrusciel M, Karlsson S, Rummakko P, Simola O, Wohlfahrt G, Hakulinen P, Vuorela A, Joensuu H, Utriainen T, Fizazi K, Oksala R. Karimaa M, et al. Among authors: chrusciel m. Mol Cancer Ther. 2022 Dec 2;21(12):1765-1776. doi: 10.1158/1535-7163.MCT-22-0115. Mol Cancer Ther. 2022. PMID: 36129801
Congenital Hypothyroidism and Hyperthyroidism Alters Adrenal Gene Expression, Development, and Function.
Patyra K, Löf C, Jaeschke H, Undeutsch H, Zheng HS, Tyystjärvi S, Puławska K, Doroszko M, Chruściel M, Loo BM, Kurkijärvi R, Zhang FP, Huang CJ, Ohlsson C, Kero A, Poutanen M, Toppari J, Paschke R, Rahman N, Huhtaniemi I, Jääskeläinen J, Kero J. Patyra K, et al. Among authors: chrusciel m. Thyroid. 2022 Apr;32(4):459-471. doi: 10.1089/thy.2021.0535. Thyroid. 2022. PMID: 35044245 Free PMC article.
Novel expression of zona pellucida 3 protein in normal testis; potential functional implications.
Pulawska K, Ponikwicka-Tyszko D, Lebiedzinska W, Guo P, Bernaczyk P, Pilaszewicz-Puza A, Li X, Chrusciel M, Lupu O, Leskinen S, Makela JA, Toppari J, Wolczynski S, Coelingh Bennink HJT, Huhtaniemi I, Rahman NA. Pulawska K, et al. Among authors: chrusciel m. Mol Cell Endocrinol. 2022 Jan 1;539:111502. doi: 10.1016/j.mce.2021.111502. Epub 2021 Nov 2. Mol Cell Endocrinol. 2022. PMID: 34736966 Free article.
Molecular mechanisms underlying mifepristone's agonistic action on ovarian cancer progression.
Ponikwicka-Tyszko D, Chrusciel M, Stelmaszewska J, Bernaczyk P, Chrusciel P, Sztachelska M, Scheinin M, Bidzinski M, Szamatowicz J, Huhtaniemi IT, Wolczynski S, Rahman NA. Ponikwicka-Tyszko D, et al. Among authors: chrusciel m. EBioMedicine. 2019 Sep;47:170-183. doi: 10.1016/j.ebiom.2019.08.035. Epub 2019 Aug 26. EBioMedicine. 2019. PMID: 31466918 Free PMC article.
Features of the fetal gonad in androgen synthesis in the postpubertal testis are preserved in complete androgen insensitivity syndrome due to a novel genetic splice site donor variant in androgen receptor gene intron 1.
Jarzabek K, Koda M, Chrusciel M, Kanczuga-Koda L, Sobczynska-Tomaszewska A, Rahman NA, Wolczynski S. Jarzabek K, et al. Among authors: chrusciel m. J Steroid Biochem Mol Biol. 2019 Oct;193:105420. doi: 10.1016/j.jsbmb.2019.105420. Epub 2019 Jul 5. J Steroid Biochem Mol Biol. 2019. PMID: 31283987
59 results