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Global chemical effects of the microbiome include new bile-acid conjugations.
Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC. Quinn RA, et al. Among authors: christy mp. Nature. 2020 Mar;579(7797):123-129. doi: 10.1038/s41586-020-2047-9. Epub 2020 Feb 26. Nature. 2020. PMID: 32103176 Free PMC article.
Dearomatization Reactions Using Phthaloyl Peroxide.
Eliasen AM, Christy M, Claussen KR, Besandre R, Thedford RP, Siegel D. Eliasen AM, et al. Org Lett. 2015 Sep 18;17(18):4420-3. doi: 10.1021/acs.orglett.5b02008. Epub 2015 Sep 1. Org Lett. 2015. PMID: 26333308
Molecular Features of CA-074 pH-Dependent Inhibition of Cathepsin B.
Yoon MC, Christy MP, Phan VV, Gerwick WH, Hook G, O'Donoghue AJ, Hook V. Yoon MC, et al. Among authors: christy mp. Biochemistry. 2022 Feb 15;61(4):228-238. doi: 10.1021/acs.biochem.1c00684. Epub 2022 Feb 4. Biochemistry. 2022. PMID: 35119840 Free PMC article.