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Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia.
Song S, Lee JY, Ermolenko L, Mazumder A, Ji S, Ryu H, Kim H, Kim DW, Lee JW, Dicato M, Christov C, Schnekenburger M, Cerella C, Gérard D, Orlikova-Boyer B, Al-Mourabit A, Diederich M. Song S, et al. Among authors: christov c. Cell Death Dis. 2020 Feb 7;11(2):109. doi: 10.1038/s41419-020-2304-8. Cell Death Dis. 2020. PMID: 32034134 Free PMC article.
The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer.
Ji S, Lee JY, Schrör J, Mazumder A, Jang DM, Chateauvieux S, Schnekenburger M, Hong CR, Christov C, Kang HJ, Lee Y, Han BW, Kim KW, Shin HY, Dicato M, Cerella C, König GM, Orlikova B, Diederich M. Ji S, et al. Among authors: christov c. Cancer Lett. 2018 Mar 1;416:109-123. doi: 10.1016/j.canlet.2017.12.011. Epub 2017 Dec 13. Cancer Lett. 2018. PMID: 29246646
The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia.
Losson H, Gajulapalli SR, Lernoux M, Lee JY, Mazumder A, Gérard D, Seidel C, Hahn H, Christov C, Dicato M, Kirsch G, Han BW, Schnekenburger M, Diederich M. Losson H, et al. Among authors: christov c. Pharmacol Res. 2020 Oct;160:105058. doi: 10.1016/j.phrs.2020.105058. Epub 2020 Jun 30. Pharmacol Res. 2020. PMID: 32619722
Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.
Florean C, Schnekenburger M, Lee JY, Kim KR, Mazumder A, Song S, Kim JM, Grandjenette C, Kim JG, Yoon AY, Dicato M, Kim KW, Christov C, Han BW, Proksch P, Diederich M. Florean C, et al. Among authors: christov c. Oncotarget. 2016 Apr 26;7(17):24027-49. doi: 10.18632/oncotarget.8210. Oncotarget. 2016. PMID: 27006469 Free PMC article.
Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells.
Lernoux M, Schnekenburger M, Losson H, Vermeulen K, Hahn H, Gérard D, Lee JY, Mazumder A, Ahamed M, Christov C, Kim DW, Dicato M, Bormans G, Han BW, Diederich M. Lernoux M, et al. Among authors: christov c. Clin Epigenetics. 2020 May 19;12(1):69. doi: 10.1186/s13148-020-00839-z. Clin Epigenetics. 2020. PMID: 32430012 Free PMC article.
134 results