Christophersen P - Search Results

1

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: christophersen p. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.

2

Potassium channel expression and function in microglia: Plasticity and possible species variations.

Nguyen HM, Blomster LV, Christophersen P, Wulff H. Nguyen HM, et al. Among authors: christophersen p. Channels (Austin). 2017 Jul 4;11(4):305-315. doi: 10.1080/19336950.2017.1300738. Epub 2017 Mar 1. Channels (Austin). 2017. PMID: 28277939 Free PMC article. Review.

3

Quantification of the functional expression of the Ca²⁺ -activated K⁺ channel K_Ca 3.1 on microglia from adult human neocortical tissue.

Blomster LV, Strøbaek D, Hougaard C, Klein J, Pinborg LH, Mikkelsen JD, Christophersen P. Blomster LV, et al. Among authors: christophersen p. Glia. 2016 Dec;64(12):2065-2078. doi: 10.1002/glia.23040. Epub 2016 Jul 29. Glia. 2016. PMID: 27470924

4

Retroviral glycoprotein-mediated immune suppression via the potassium channel K_Ca3.1 - A new strategy for amelioration of inflammatory bowel diseases.

Laska MJ, Moeller JB, Graversen JH, Strøbæk D, Blomster L, Christophersen P, Bahrami S. Laska MJ, et al. Among authors: christophersen p. Clin Immunol. 2022 Sep;242:109081. doi: 10.1016/j.clim.2022.109081. Epub 2022 Jul 26. Clin Immunol. 2022. PMID: 35905828 Free article.

5

NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.

Strøbæk D, Brown DT, Jenkins DP, Chen YJ, Coleman N, Ando Y, Chiu P, Jørgensen S, Demnitz J, Wulff H, Christophersen P. Strøbæk D, et al. Among authors: christophersen p. Br J Pharmacol. 2013 Jan;168(2):432-44. doi: 10.1111/j.1476-5381.2012.02143.x. Br J Pharmacol. 2013. PMID: 22891655 Free PMC article.

6

Antibodies and venom peptides: new modalities for ion channels.

Wulff H, Christophersen P, Colussi P, Chandy KG, Yarov-Yarovoy V. Wulff H, et al. Among authors: christophersen p. Nat Rev Drug Discov. 2019 May;18(5):339-357. doi: 10.1038/s41573-019-0013-8. Nat Rev Drug Discov. 2019. PMID: 30728472 Free PMC article. Review.

7

Voltage-independent KCNQ4 currents induced by (+/-)BMS-204352.

Schrøder RL, Strøbaek D, Olesen SP, Christophersen P. Schrøder RL, et al. Among authors: christophersen p. Pflugers Arch. 2003 Aug;446(5):607-16. doi: 10.1007/s00424-003-1116-x. Epub 2003 Jul 8. Pflugers Arch. 2003. PMID: 12851819

8

Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime).

Strøbaek D, Teuber L, Jørgensen TD, Ahring PK, Kjaer K, Hansen RS, Olesen SP, Christophersen P, Skaaning-Jensen B. Strøbaek D, et al. Among authors: christophersen p. Biochim Biophys Acta. 2004 Oct 11;1665(1-2):1-5. doi: 10.1016/j.bbamem.2004.07.006. Biochim Biophys Acta. 2004. PMID: 15471565 Free article.

9

Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons.

Strøbaek D, Hougaard C, Johansen TH, Sørensen US, Nielsen EØ, Nielsen KS, Taylor RD, Pedarzani P, Christophersen P. Strøbaek D, et al. Among authors: christophersen p. Mol Pharmacol. 2006 Nov;70(5):1771-82. doi: 10.1124/mol.106.027110. Epub 2006 Aug 22. Mol Pharmacol. 2006. PMID: 16926279

10

Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels.

Sørensen US, Strøbaek D, Christophersen P, Hougaard C, Jensen ML, Nielsen EØ, Peters D, Teuber L. Sørensen US, et al. Among authors: christophersen p. J Med Chem. 2008 Dec 11;51(23):7625-34. doi: 10.1021/jm800809f. J Med Chem. 2008. PMID: 18998663

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